Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDSPVLQSAY DPSGQYLCYV TVALDKQRVG VQPTQRATSS GVDTVWNENF LYLEDSKLKV

70 80 90 100 110 120
TCLKWVNLAS SDTVAIILGM NNGEIWLYSV LANEVTYKFT TGNSYEIKDI DLMGNQLWCI

130 140 150 160 170 180
DSSDAFYQFD LLQFKLLQHF RINNCVQLNK LTIVPAGDSV AQLLVASHSI SLIDIEEKKV

190 200 210 220 230 240
VMTFPGHVSP VSTLQVITNE FFISGAEGDR FLNVYDIHSG MTKCVLVAES DIKELSHSGQ

250 260 270 280 290 300
ADSIAVTTED GSLEIFVDPL VSSSTKKRGN KSKKSSKKIQ IVSKDGRKVP IYNAFINKDL

310 320 330 340 350 360
LNVSWLQNAT MPYFKNLQWR EIPNEYTVEI SLNWNNKNKS ADRDLHGKDL ASATNYVEGN

370 380 390 400 410 420
ARVTSGDNFK HVDDAIKSWE RELTSLEQEQ AKPPQANELL TETFGDKLES STVARISGKK

430 440 450 460 470 480
TNLKGSNLKT ATTTGTVTVI LSQALQSNDH SLLETVLNNR DERVIRDTIF RLKPALAVIL

490 500 510 520 530 540
LERLAERIAR QTHRQGPLNV WVKWCLIIHG GYLVSIPNLM STLSSLHSTL KRRSDLLPRL

550 560 570 580 590 600
LALDARLDCT INKFKTLNYE AGDIHSSEPV VEEDEDDVEY NEELDDAGLI EDGEESYGSE

610 620 630 640
EEEEGDSDNE EEQKHTSSKQ DGRLETEQSD GEEEAGYSDV EME


References and documentation are available.

Number of amino acids: 643 Molecular weight: 72001.62 Theoretical pI: 4.82
Amino acid composition: 
Ala (A) 35 5.4% Arg (R) 24 3.7% Asn (N) 39 6.1% Asp (D) 46 7.2% Cys (C) 7 1.1% Gln (Q) 26 4.0% Glu (E) 54 8.4% Gly (G) 34 5.3% His (H) 13 2.0% Ile (I) 36 5.6% Leu (L) 69 10.7% Lys (K) 41 6.4% Met (M) 8 1.2% Phe (F) 17 2.6% Pro (P) 17 2.6% Ser (S) 61 9.5% Thr (T) 41 6.4% Trp (W) 10 1.6% Tyr (Y) 18 2.8% Val (V) 47 7.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 100 Total number of positively charged residues (Arg + Lys): 65 Atomic composition: Carbon C 3164 Hydrogen H 5011 Nitrogen N 857 Oxygen O 1029 Sulfur S 15 Formula: C3164H5011N857O1029S15 Total number of atoms: 10076 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 82195 Abs 0.1% (=1 g/l) 1.142, assuming all pairs of Cys residues form cystines Ext. coefficient 81820 Abs 0.1% (=1 g/l) 1.136, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.77 This classifies the protein as unstable. Aliphatic index: 90.33 Grand average of hydropathicity (GRAVY): -0.424