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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDSQVEGKIS PSQKESSSTS GLVSPSEDGP AHQKIHRDQL SVDQIKKIRE ERAQKRQVRR

70 80 90 100 110 120
NSLISQGKDP DFPTPDLQFI ERPFLPINHD NSKGLTPATI QVTQDSLDVK IMTYNTLAQT

130 140 150 160 170 180
LIRRDFFPES GPALKWHKRS KVLVHELKKY RPDVVSLQEV DYNELNFWQE NFHKLGFDVI

190 200 210 220 230 240
FKRHEGKTHG LLVAWNNKKF QLDNDWMLDY DNILAGNVIS ARTRTKNIAL IISLYFKGIT

250 260 270 280 290 300
DSSSRGIIVA NTHLFWHPFG VFERLRQSYL VLQKIQEIKA CSKYNGWHSL LMGDFNTEPE

310 320 330 340 350 360
EPPYLAITKR PLILKGPIRA MVECSLAYRY SKKRNGEESD QDDEECDEKS RGEGHSDQPQ

370 380 390 400 410 420
NPKPESFTAT KEEKALVNQL VALHNSLHVK GVSLYGIGYG KVHPENANGS HGEPGLSNWA

430 440 450 460 470 480
NTWCGLLDYI FYIEGDHNQD TRQKEPLNAF EGNNNVKIIG YLRMPCAQEM PKHSQPFEGE

490 500
YASDHISLMC QIRLFFGGEK VHSLK


References and documentation are available.

Number of amino acids: 505 Molecular weight: 57742.26 Theoretical pI: 7.06
Amino acid composition: 
Ala (A) 22 4.4% Arg (R) 25 5.0% Asn (N) 29 5.7% Asp (D) 29 5.7% Cys (C) 6 1.2% Gln (Q) 27 5.3% Glu (E) 36 7.1% Gly (G) 33 6.5% His (H) 20 4.0% Ile (I) 31 6.1% Leu (L) 45 8.9% Lys (K) 39 7.7% Met (M) 8 1.6% Phe (F) 21 4.2% Pro (P) 27 5.3% Ser (S) 39 7.7% Thr (T) 19 3.8% Trp (W) 8 1.6% Tyr (Y) 16 3.2% Val (V) 25 5.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 65 Total number of positively charged residues (Arg + Lys): 64 Atomic composition: Carbon C 2571 Hydrogen H 3999 Nitrogen N 723 Oxygen O 766 Sulfur S 14 Formula: C2571H3999N723O766S14 Total number of atoms: 8073 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 68215 Abs 0.1% (=1 g/l) 1.181, assuming all pairs of Cys residues form cystines Ext. coefficient 67840 Abs 0.1% (=1 g/l) 1.175, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.61 This classifies the protein as unstable. Aliphatic index: 77.41 Grand average of hydropathicity (GRAVY): -0.667