ProtParam
User-provided sequence:
10 20 30 40 50 60
MDSRTVGILG GGQLGRMIVE AANRLNIKTV ILDAENSPAK QISNSNDHVN GSFSNPLDIE
70 80 90 100 110 120
KLAEKCDVLT IEIEHVDVPT LKNLQVKHPK LKIYPSPETI RLIQDKYIQK EHLIKNGIAV
130 140 150 160 170 180
TQSVPVEQAS ETSLLNVGRD LGFPFVLKSR TLAYDGRGNF VVKNKEMIPE ALEVLKDRPL
190 200 210 220 230 240
YAEKWAPFTK ELAVMIVRSV NGLVFSYPIV ETIHKDNICD LCYAPARVPD SVQLKAKLLA
250 260 270 280 290 300
ENAIKSFPGC GIFGVEMFYL ETGELLINEI APRPHNSGHY TIDACVTSQF EAHLRSILDL
310 320 330 340 350 360
PMPKNFTSFS TITTNAIMLN VLGDKHTKDK ELETCERALA TPGSSVYLYG KESRPNRKVG
370 380 390 400 410 420
HINIIASSMA ECEQRLNYIT GRTDIPIKIS VAQKLDLEAM VKPLVGIIMG SDSDLPVMSA
430 440 450 460 470 480
ACAVLKDFGV PFEVTIVSAH RTPHRMSAYA ISASKRGIKT IIAGAGGAAH LPGMVAAMTP
490 500 510 520 530 540
LPVIGVPVKG SCLDGVDSLH SIVQMPRGVP VATVAINNST NAALLAVRLL GAYDSSYTTK
550 560 570
MEQFLLKQEE EVLVKAQKLE TVGYEAYLEN K
References and
documentation are available.
Number of amino acids: 571
Molecular weight: 62339.30
Theoretical pI: 6.93
Total number of negatively charged residues (Asp + Glu): 62
Total number of positively charged residues (Arg + Lys): 61
Atomic composition:
Carbon C 2777
Hydrogen H 4501
Nitrogen N 747
Oxygen O 824
Sulfur S 25
Formula: C
2777H
4501N
747O
824S
25
Total number of atoms: 8874
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 29840
Abs 0.1% (=1 g/l) 0.479, assuming all pairs of Cys residues form cystines
Ext. coefficient 29340
Abs 0.1% (=1 g/l) 0.471, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 40.99
This classifies the protein as unstable.
Aliphatic index: 101.59
Grand average of hydropathicity (GRAVY): -0.004