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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDSVTNFFWN DTYNAGTPTR STLKGKKVQN GIDGKSQAKK ESISSGSRTS DPTRGSLPSS

70 80 90 100 110 120
SGQPTSGGGF PSTSNIQKMM ADTLVEKIIK MALPPSSKTA VDTIHHRMVA GKERPKLSVQ

130 140 150 160 170 180
ITSRNFIQMN SRLGVPFMIM DELIKILNWT NPAYTVSIMF LYTLIILKPF QMLSSLPIFY

190 200 210 220 230 240
LLFCVMVPQY LYIHKPNPTS YLDNNQTPAQ GPPLRRPEVP KPVPELSQEF VLNLTDLQNH

250 260 270 280 290 300
MLLYVKFYDF TLLILQKFAF FTNEAISSFY FIVLLIIATL NFLYMDKFIK LIPMRPVLIL

310 320 330 340 350 360
LGWGFFIASH PSNREYLLTK LNSEETRLKT LTISTNLESK ILQHLKLIEA REHRLVMIFE

370 380 390 400 410 420
IQKYLPEYKE WRPVGFSDDD YSLFSSLRIY QRRIEENSVK SLEEIEPPKD WEWEANSHWV

430 440 450 460 470 480
LDLDPKEWVE DEFIQYVEID SETKWVYDLN LDGQRGSYRR RMWTNSCVRK KLDSGISSNL

490 500 510 520 530 540
GEEEVVNPLR EETYRQGVHG VTKGSMSGGL THSSDDDRAD EESINGTIPN LNNIDADASY

550
PSIEELTDTL NSTI


References and documentation are available.

Number of amino acids: 554 Molecular weight: 63542.68 Theoretical pI: 5.81
Amino acid composition: 
Ala (A) 17 3.1% Arg (R) 26 4.7% Asn (N) 30 5.4% Asp (D) 29 5.2% Cys (C) 2 0.4% Gln (Q) 19 3.4% Glu (E) 38 6.9% Gly (G) 26 4.7% His (H) 10 1.8% Ile (I) 41 7.4% Leu (L) 60 10.8% Lys (K) 33 6.0% Met (M) 17 3.1% Phe (F) 25 4.5% Pro (P) 33 6.0% Ser (S) 53 9.6% Thr (T) 36 6.5% Trp (W) 10 1.8% Tyr (Y) 21 3.8% Val (V) 28 5.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 67 Total number of positively charged residues (Arg + Lys): 59 Atomic composition: Carbon C 2867 Hydrogen H 4474 Nitrogen N 744 Oxygen O 848 Sulfur S 19 Formula: C2867H4474N744O848S19 Total number of atoms: 8952 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 86415 Abs 0.1% (=1 g/l) 1.360, assuming all pairs of Cys residues form cystines Ext. coefficient 86290 Abs 0.1% (=1 g/l) 1.358, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.94 This classifies the protein as unstable. Aliphatic index: 88.83 Grand average of hydropathicity (GRAVY): -0.330