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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDTEADLFYR QLPKVELHAH LNGSVSFETM EKLIKRKPHL NIEHSMTAIR RGQRRTLDEC

70 80 90 100 110 120
FQVFKVIHQL VDSEEDILMV AKSVIQEFAA DGVKYLELRS TPREVTETGL SKQRYIETVL

130 140 150 160 170 180
EAIRQCKQEG VDIDVRFLVA VDRRHGPEVA MQTVKLAEDF LLSSDGTVVG LDLSGDPTVG

190 200 210 220 230 240
HGKDLLAALQ KAKNCGLKLA LHLSEVPSQI DETELLLNLP PDRIGHGTFL HPDVGGSDSL

250 260 270 280 290 300
VDKVCKQNIP IEICLTSNVK GQTVPSYDKH HFKYWYNRGH PCVLCTDDKG VFCTDLSQEY

310 320 330 340
QLAASTFGLT KEAVWILSQQ AIGYTFAPEP IKQRLEKTWA ELKQQILQ


References and documentation are available.

Number of amino acids: 348 Molecular weight: 39189.89 Theoretical pI: 5.83
Amino acid composition: 
Ala (A) 20 5.7% Arg (R) 16 4.6% Asn (N) 7 2.0% Asp (D) 23 6.6% Cys (C) 8 2.3% Gln (Q) 21 6.0% Glu (E) 26 7.5% Gly (G) 21 6.0% His (H) 13 3.7% Ile (I) 18 5.2% Leu (L) 41 11.8% Lys (K) 24 6.9% Met (M) 5 1.4% Phe (F) 12 3.4% Pro (P) 14 4.0% Ser (S) 19 5.5% Thr (T) 21 6.0% Trp (W) 3 0.9% Tyr (Y) 8 2.3% Val (V) 28 8.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 40 Atomic composition: Carbon C 1742 Hydrogen H 2779 Nitrogen N 477 Oxygen O 523 Sulfur S 13 Formula: C1742H2779N477O523S13 Total number of atoms: 5534 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 28920 Abs 0.1% (=1 g/l) 0.738, assuming all pairs of Cys residues form cystines Ext. coefficient 28420 Abs 0.1% (=1 g/l) 0.725, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.77 This classifies the protein as stable. Aliphatic index: 95.20 Grand average of hydropathicity (GRAVY): -0.279