ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDTGGNSLAS GPDGVKRKVC YFYDPEVGNY YYGQGHPMKP HRIRMTHALL AHYGLLQHMQ 

        70         80         90        100        110        120 
VLKPFPARDR DLCRFHADDY VSFLRSITPE TQQDQIRQLK RFNVGEDCPV FDGLYSFCQT 

       130        140        150        160        170        180 
YAGGSVGGSV KLNHGLCDIA INWAGGLHHA KKCEASGFCY VNDIVLAILE LLKQHERVLY 

       190        200        210        220        230        240 
VDIDIHHGDG VEEAFYATDR VMTVSFHKFG DYFPGTGHIQ DIGYGSGKYY SLNVPLDDGI 

       250        260        270        280        290        300 
DDESYHLLFK PIMGKVMEIF RPGAVVLQCG ADSLSGDRLG CFNLSIKGHA ECVKFMRSFN 

       310        320        330        340        350        360 
VPLLLLGGGG YTIRNVARCW CYETGVALGV EVEDKMPEHE YYEYFGPDYT LHVAPSNMEN 

       370        380        390        400        410        420 
KNSRQMLEEI RNDLLHNLSK LQHAPSVPFQ ERPPDTETPE VDEDQEDGDK RWDPDSDMDV 

       430        440        450        460        470        480 
DDDRKPIPSR VKREAVEPDT KDKDGLKGIM ERGKGCEVEV DESGSTKVTG VNPVGVEEAS 

       490        500 
VKMEEEGTNK GGAEQAFPPK T 

References and documentation are available.

Number of amino acids: 501

Molecular weight: 56022.96

Theoretical pI: 5.14

Amino acid composition: 
Ala (A)  24	  4.8%
Arg (R)  24	  4.8%
Asn (N)  17	  3.4%
Asp (D)  43	  8.6%
Cys (C)  13	  2.6%
Gln (Q)  16	  3.2%
Glu (E)  37	  7.4%
Gly (G)  51	 10.2%
His (H)  20	  4.0%
Ile (I)  19	  3.8%
Leu (L)  38	  7.6%
Lys (K)  29	  5.8%
Met (M)  14	  2.8%
Phe (F)  20	  4.0%
Pro (P)  28	  5.6%
Ser (S)  25	  5.0%
Thr (T)  18	  3.6%
Trp (W)   3	  0.6%
Tyr (Y)  23	  4.6%
Val (V)  39	  7.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 80
Total number of positively charged residues (Arg + Lys): 53

Atomic composition:

Carbon      C	      2470
Hydrogen    H	      3788
Nitrogen    N	       678
Oxygen      O	       761
Sulfur      S	        27

Formula: C2470H3788N678O761S27
Total number of atoms: 7724

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    51520
Abs 0.1% (=1 g/l)   0.920, assuming all pairs of Cys residues form cystines


Ext. coefficient    50770
Abs 0.1% (=1 g/l)   0.906, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.88
This classifies the protein as stable.



Aliphatic index: 71.74

Grand average of hydropathicity (GRAVY): -0.517