ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDTVGTDAAA ASINERRFAQ STSPKVSVKS QDSLFLITYS NMQQTVVQAS LADRYPSLKK 

        70         80         90        100        110        120 
LNILLYIDIP TIDYYNDEMT HNKLSRLNKR FKLHRLRNSI AQSFSNTSTA EDNDKFWEEL 

       130        140        150        160        170        180 
KSLISSRSTP ENKFDLNVLV SSSGSLRYVE TIRFLVEKLF NSFKDLYVQK KLNLCFQINV 

       190        200        210        220        230        240 
SPTSLKWFST FLNAELLNLK IINWQNIGSF TKTIQNSKSL PFKEYYTKLN EKFTGSNQSN 

       250        260        270        280        290        300 
GSMQDQTVLD SIVIVTNSTG VKALLTLLSD HPLTSLISQE SIKALHEYSD AVNEDKGDDQ 

       310        320        330        340        350        360 
SNTSLKRNSS SLLNFQNSVL TSNKDKSVRI RSLSINRKSN RAHMFKTNES ITTIPSTSIN 

       370        380        390        400        410        420 
NLIGQESNLR KQPSGTALHL QSHLHPHSRS QSYSSSNMSR SPSPFPYGKT PSNDELVYDE 

       430        440        450        460        470        480 
LNNQINEVQD RAKNEEIVLY NNNNYDDYTK ERGEQEQDRT SYADEYGFNY DDEEGGNEDN 

       490        500        510        520        530        540 
YDDDEDDDDD DDDDDESDDE GLSFYAPSIL SRSGSSTDVL SSGIDSMAKN SKETRGRFRS 

       550        560        570        580        590        600 
LSLMDPALQK PFNQKFPNSQ QPDSAGASSP KRSTSSNHFT NVYVHDGDFD GTDTINNKKN 

       610        620        630        640        650        660 
LSSATLIKRK SLMNRNLAPS ISNGLIPPEF ISRISTPSTS ASSSNSSLND MSTVSNAFSK 

       670        680        690        700        710        720 
LLNDTSKKQK FLNSPIPQHT QQASPLLMRN NSNSNLLFEK NLINKSFEEL RRQPSVNLFS 

       730        740        750        760        770        780 
TLMNGNMEKN GLALNFKSRT PTDALMANSI KNSNNSSHRL LNLEEEDQIM SGSLPKERED 

       790        800        810        820        830        840 
DNDSTNSTIV PNHPDNDNYN DNDNDNNTGI NSNNFNLNLY DDNDSAGFTD VTTEGVKYSN 

       850        860        870 
SNSTVTKPVY KKAVTLDLYG EDDMDNMGGW VLGGNAR 

References and documentation are available.

Number of amino acids: 877

Molecular weight: 98330.84

Theoretical pI: 5.18

Amino acid composition: 
Ala (A)  33	  3.8%
Arg (R)  36	  4.1%
Asn (N) 100	 11.4%
Asp (D)  72	  8.2%
Cys (C)   1	  0.1%
Gln (Q)  34	  3.9%
Glu (E)  44	  5.0%
Gly (G)  33	  3.8%
His (H)  14	  1.6%
Ile (I)  40	  4.6%
Leu (L)  84	  9.6%
Lys (K)  56	  6.4%
Met (M)  17	  1.9%
Phe (F)  34	  3.9%
Pro (P)  33	  3.8%
Ser (S) 126	 14.4%
Thr (T)  56	  6.4%
Trp (W)   4	  0.5%
Tyr (Y)  27	  3.1%
Val (V)  33	  3.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 116
Total number of positively charged residues (Arg + Lys): 92

Atomic composition:

Carbon      C	      4236
Hydrogen    H	      6669
Nitrogen    N	      1207
Oxygen      O	      1453
Sulfur      S	        18

Formula: C4236H6669N1207O1453S18
Total number of atoms: 13583

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    62230
Abs 0.1% (=1 g/l)   0.633, assuming all pairs of Cys residues form cystines


Ext. coefficient    62230
Abs 0.1% (=1 g/l)   0.633, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 44.26
This classifies the protein as unstable.



Aliphatic index: 69.82

Grand average of hydropathicity (GRAVY): -0.818