ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDVEKDVLDV YIKNLENQIG NKRYFLKQAQ GAIDEITKRS LDTEGKPVNS EVFTELLRKP 

        70         80         90        100        110        120 
MFFSERADPI GFSLTSNFLS LRAQSSSEWL SLMNDQSVDQ KAMLLLQNNI NSDLKELLRK 

       130        140        150        160        170        180 
LQHQMTIMDS KKQDHAHIRT RKARNKELWD SLADFLKGYL VPNLDDNDES IDSLTNEVML 

       190        200        210        220        230 
LMKRLIEHDL NLTLNDFSSK TIPIYRLLLR ANIITVIEGS TNPGTKYIKL IDFNETSLT 

References and documentation are available.

Number of amino acids: 239

Molecular weight: 27567.54

Theoretical pI: 5.66

Amino acid composition: 
Ala (A)   9	  3.8%
Arg (R)  12	  5.0%
Asn (N)  18	  7.5%
Asp (D)  20	  8.4%
Cys (C)   0	  0.0%
Gln (Q)  10	  4.2%
Glu (E)  15	  6.3%
Gly (G)   7	  2.9%
His (H)   4	  1.7%
Ile (I)  17	  7.1%
Leu (L)  35	 14.6%
Lys (K)  19	  7.9%
Met (M)   8	  3.3%
Phe (F)   9	  3.8%
Pro (P)   6	  2.5%
Ser (S)  20	  8.4%
Thr (T)  14	  5.9%
Trp (W)   2	  0.8%
Tyr (Y)   5	  2.1%
Val (V)   9	  3.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 35
Total number of positively charged residues (Arg + Lys): 31

Atomic composition:

Carbon      C	      1219
Hydrogen    H	      1972
Nitrogen    N	       332
Oxygen      O	       377
Sulfur      S	         8

Formula: C1219H1972N332O377S8
Total number of atoms: 3908

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    18450
Abs 0.1% (=1 g/l)   0.669

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.91
This classifies the protein as stable.



Aliphatic index: 99.54

Grand average of hydropathicity (GRAVY): -0.435