ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDVPRPAFKC FDDDGRLKRS GTVWTASAHI ITAVIGSGVL SLAWAIGQLG WIAGPTVMLL 

        70         80         90        100        110        120 
FSFVTYYSST LLSDCYRTGD PVSGKRNYTY MDAVRSILGG FRFKICGLIQ YLNLFGITVG 

       130        140        150        160        170        180 
YTIAASISMM AIKRSNCFHE SGGKNPCHMS SNPYMIMFGV TEILLSQIKD FDQIWWLSIV 

       190        200        210        220        230        240 
AAIMSFTYSA IGLALGIIQV AANGVVKGSL TGISIGAVTQ TQKIWRTFQA LGDIAFAYSY 

       250        260        270        280        290        300 
SVVLIEIQDT VRSPPAESKT MKIATRISIA VTTTFYMLCG CMGYAAFGDK APGNLLTGFG 

       310        320        330        340        350        360 
FYNPFWLLDV ANAAIVIHLV GAYQVFAQPI FAFIEKQAAA RFPDSDLVTK EYEIRIPGFR 

       370        380        390        400        410        420 
SPYKVNVFRA VYRSGFVVLT TVISMLMPFF NDVVGILGAL GFWPLTVYFP VEMYIRQRKV 

       430        440        450        460 
ERWSMKWVCL QMLSCGCLMI TLVAGVGSIA GVMLDLKVYK PFKTTY 

References and documentation are available.

Number of amino acids: 466

Molecular weight: 51428.53

Theoretical pI: 9.21

Amino acid composition: 
Ala (A)  40	  8.6%
Arg (R)  19	  4.1%
Asn (N)  11	  2.4%
Asp (D)  17	  3.6%
Cys (C)  10	  2.1%
Gln (Q)  14	  3.0%
Glu (E)   9	  1.9%
Gly (G)  40	  8.6%
His (H)   4	  0.9%
Ile (I)  41	  8.8%
Leu (L)  38	  8.2%
Lys (K)  20	  4.3%
Met (M)  19	  4.1%
Phe (F)  30	  6.4%
Pro (P)  18	  3.9%
Ser (S)  34	  7.3%
Thr (T)  30	  6.4%
Trp (W)  10	  2.1%
Tyr (Y)  22	  4.7%
Val (V)  40	  8.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 26
Total number of positively charged residues (Arg + Lys): 39

Atomic composition:

Carbon      C	      2374
Hydrogen    H	      3668
Nitrogen    N	       586
Oxygen      O	       630
Sulfur      S	        29

Formula: C2374H3668N586O630S29
Total number of atoms: 7287

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    88405
Abs 0.1% (=1 g/l)   1.719, assuming all pairs of Cys residues form cystines


Ext. coefficient    87780
Abs 0.1% (=1 g/l)   1.707, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.80
This classifies the protein as stable.



Aliphatic index: 99.59

Grand average of hydropathicity (GRAVY): 0.491