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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDVTRLLLAT LVGFLCFLTV HSHLVFEETL GDDRSLKSNS SINSLDFSSV SIVALNKKSK

70 80 90 100 110 120
KISRKEAEKR KRSSKKKASI KKVARPPPPS PCVATRDSCK PPAPACCNPC ASCQCRFFGS

130
ACTCRVLNPN C


References and documentation are available.

Number of amino acids: 131 Molecular weight: 14275.75 Theoretical pI: 9.62
Amino acid composition: 
Ala (A) 10 7.6% Arg (R) 9 6.9% Asn (N) 6 4.6% Asp (D) 5 3.8% Cys (C) 11 8.4% Gln (Q) 1 0.8% Glu (E) 4 3.1% Gly (G) 3 2.3% His (H) 2 1.5% Ile (I) 4 3.1% Leu (L) 12 9.2% Lys (K) 14 10.7% Met (M) 1 0.8% Phe (F) 6 4.6% Pro (P) 10 7.6% Ser (S) 18 13.7% Thr (T) 6 4.6% Trp (W) 0 0.0% Tyr (Y) 0 0.0% Val (V) 9 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 9 Total number of positively charged residues (Arg + Lys): 23 Atomic composition: Carbon C 616 Hydrogen H 1025 Nitrogen N 183 Oxygen O 181 Sulfur S 12 Formula: C616H1025N183O181S12 Total number of atoms: 2017 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 625 Abs 0.1% (=1 g/l) 0.044, assuming all pairs of Cys residues form cystines Ext. coefficient 0 Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 54.22 This classifies the protein as unstable. Aliphatic index: 75.19 Grand average of hydropathicity (GRAVY): -0.211