ProtParam
User-provided sequence:
10 20 30 40 50 60
MDWAIKAARK KTQRKPGSTR SIIETLDDLN NLTTDAHSEI NQRLYESSEW LRNNVYMNTL
70 80 90 100 110 120
KYEDKKMEES LISPENTHNK MDVEFPKMKG EYELSNSQND AAKDVTKTPR NGLHNDKSIT
130 140 150 160 170 180
PKSLRRKEVT EGMNRFSIHD TNKSPVEPLN SVKVDANESE KSSPWSPYKV EKVLRESSKT
190 200 210 220 230 240
SESPINTKRF DNQTWAAKEE MENEPILQAL KKAESVKVKP PPNSGIARSQ RRSNMFVPLP
250 260 270 280 290 300
NKDPLIIQHI PPTKSSGSIP KVRTVKESPI AFKKKSTINS PAIRAVENSD TAGSTKASSV
310 320 330 340 350 360
FDRLSSIPTK SFENKISRGN VGHKYSSSSI DLTGSPMKKV SQKFKSINST DTDMQEALRD
370 380 390 400 410 420
IFSVKNKITK NNSPKGKNSR KSSIPRFDKT SLKLTTHKKL AIIAEQKKKS KHSSDVHKTG
430 440 450 460 470 480
SRPHSISPTK ISVDSSSPSK EVKNYYQSPV RGYLRPTKAS ISPNKNKNLT TSQTPHRLKI
490 500 510 520 530 540
KEKTLRKLSP NIADISKPES RKSKNYRLTN LQLLPPAEAE RDDLKKKFDK RLSGIMRSQQ
550 560 570 580 590 600
EHHRRKQEKQ KRMSHLEQDL KKQTSFSNDY KDIRLKESLA PFDNHVRDTI NKNTAFSTDN
610 620 630 640 650 660
ILATINTVDH REIIGNVTPK IASVNDSLPE INTDSEDEAS VTLAAWAKSP YLQEQLIRQQ
670 680 690
DINPQTIFGP IPPLHTDEIF PNPRLNRLKP RQIVPKRS
References and
documentation are available.
Number of amino acids: 698
Molecular weight: 79185.73
Theoretical pI: 9.92
Total number of negatively charged residues (Asp + Glu): 82
Total number of positively charged residues (Arg + Lys): 128
Atomic composition:
Carbon C 3450
Hydrogen H 5648
Nitrogen N 1024
Oxygen O 1083
Sulfur S 12
Formula: C
3450H
5648N
1024O
1083S
12
Total number of atoms: 11217
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 45380
Abs 0.1% (=1 g/l) 0.573
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 54.68
This classifies the protein as unstable.
Aliphatic index: 68.04
Grand average of hydropathicity (GRAVY): -1.011