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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDWAIKAARK KTQRKPGSTR SIIETLDDLN NLTTDAHSEI NQRLYESSEW LRNNVYMNTL

70 80 90 100 110 120
KYEDKKMEES LISPENTHNK MDVEFPKMKG EYELSNSQND AAKDVTKTPR NGLHNDKSIT

130 140 150 160 170 180
PKSLRRKEVT EGMNRFSIHD TNKSPVEPLN SVKVDANESE KSSPWSPYKV EKVLRESSKT

190 200 210 220 230 240
SESPINTKRF DNQTWAAKEE MENEPILQAL KKAESVKVKP PPNSGIARSQ RRSNMFVPLP

250 260 270 280 290 300
NKDPLIIQHI PPTKSSGSIP KVRTVKESPI AFKKKSTINS PAIRAVENSD TAGSTKASSV

310 320 330 340 350 360
FDRLSSIPTK SFENKISRGN VGHKYSSSSI DLTGSPMKKV SQKFKSINST DTDMQEALRD

370 380 390 400 410 420
IFSVKNKITK NNSPKGKNSR KSSIPRFDKT SLKLTTHKKL AIIAEQKKKS KHSSDVHKTG

430 440 450 460 470 480
SRPHSISPTK ISVDSSSPSK EVKNYYQSPV RGYLRPTKAS ISPNKNKNLT TSQTPHRLKI

490 500 510 520 530 540
KEKTLRKLSP NIADISKPES RKSKNYRLTN LQLLPPAEAE RDDLKKKFDK RLSGIMRSQQ

550 560 570 580 590 600
EHHRRKQEKQ KRMSHLEQDL KKQTSFSNDY KDIRLKESLA PFDNHVRDTI NKNTAFSTDN

610 620 630 640 650 660
ILATINTVDH REIIGNVTPK IASVNDSLPE INTDSEDEAS VTLAAWAKSP YLQEQLIRQQ

670 680 690
DINPQTIFGP IPPLHTDEIF PNPRLNRLKP RQIVPKRS


References and documentation are available.

Number of amino acids: 698 Molecular weight: 79185.73 Theoretical pI: 9.92
Amino acid composition: 
Ala (A) 32 4.6% Arg (R) 42 6.0% Asn (N) 50 7.2% Asp (D) 38 5.4% Cys (C) 0 0.0% Gln (Q) 25 3.6% Glu (E) 44 6.3% Gly (G) 16 2.3% His (H) 17 2.4% Ile (I) 47 6.7% Leu (L) 45 6.4% Lys (K) 86 12.3% Met (M) 12 1.7% Phe (F) 16 2.3% Pro (P) 49 7.0% Ser (S) 86 12.3% Thr (T) 47 6.7% Trp (W) 5 0.7% Tyr (Y) 12 1.7% Val (V) 29 4.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 82 Total number of positively charged residues (Arg + Lys): 128 Atomic composition: Carbon C 3450 Hydrogen H 5648 Nitrogen N 1024 Oxygen O 1083 Sulfur S 12 Formula: C3450H5648N1024O1083S12 Total number of atoms: 11217 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 45380 Abs 0.1% (=1 g/l) 0.573 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 54.68 This classifies the protein as unstable. Aliphatic index: 68.04 Grand average of hydropathicity (GRAVY): -1.011