ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDYIKKAIWG PDPKEQQRRI RSVLRKNGRN IEKSLRELTV LQNKTQQLIK KSAKKNDVRT 

        70         80         90        100        110        120 
VRLYAKELYQ INKQYDRMYT SRAQLDSVRM KIDEAIRMNT LSNQMADSAG LMREVNSLVR 

       130        140        150        160        170        180 
LPQLRNTMIE LEKELMKSGI ISEMVDDTME SVGDVGEEMD EAVDEEVNKI VEQYTNEKFK 

       190        200        210        220 
NVDQVPTVEL AANEEEQEIP DEKVDEEADR MVNEMRERLR ALQN 

References and documentation are available.

Number of amino acids: 224

Molecular weight: 26241.85

Theoretical pI: 5.14

Amino acid composition: 
Ala (A)  12	  5.4%
Arg (R)  19	  8.5%
Asn (N)  15	  6.7%
Asp (D)  16	  7.1%
Cys (C)   0	  0.0%
Gln (Q)  14	  6.2%
Glu (E)  28	 12.5%
Gly (G)   6	  2.7%
His (H)   0	  0.0%
Ile (I)  13	  5.8%
Leu (L)  18	  8.0%
Lys (K)  19	  8.5%
Met (M)  13	  5.8%
Phe (F)   1	  0.4%
Pro (P)   5	  2.2%
Ser (S)  11	  4.9%
Thr (T)   9	  4.0%
Trp (W)   1	  0.4%
Tyr (Y)   6	  2.7%
Val (V)  18	  8.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 44
Total number of positively charged residues (Arg + Lys): 38

Atomic composition:

Carbon      C	      1119
Hydrogen    H	      1860
Nitrogen    N	       330
Oxygen      O	       368
Sulfur      S	        13

Formula: C1119H1860N330O368S13
Total number of atoms: 3690

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    14440
Abs 0.1% (=1 g/l)   0.550

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.25
This classifies the protein as unstable.



Aliphatic index: 82.63

Grand average of hydropathicity (GRAVY): -0.883