ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDYQNRAGVR FGGGGVAGYQ ETNAARRERL RKLALETIDL SKDPYLMKNH LGTFECRLCL 

        70         80         90        100        110        120 
TTHANENSYL THTQGKKHQT NLARRQALEN KKSQENAPQV LLGISQSHVQ VKKSVVKIGR 

       130        140        150        160        170        180 
PGYKVSKIRE AESGKFGLRF QIKYPDIEVN AKPRYRIMSA YEQRVEAPDR KFQYLVVAAE 

       190        200        210 
PYESIAFKID RAPGKFWSYW DAPTYTIQFF YNLTKIS 

References and documentation are available.

Number of amino acids: 217

Molecular weight: 24986.53

Theoretical pI: 9.79

Amino acid composition: 
Ala (A)  18	  8.3%
Arg (R)  17	  7.8%
Asn (N)  10	  4.6%
Asp (D)   7	  3.2%
Cys (C)   2	  0.9%
Gln (Q)  13	  6.0%
Glu (E)  14	  6.5%
Gly (G)  14	  6.5%
His (H)   5	  2.3%
Ile (I)  11	  5.1%
Leu (L)  16	  7.4%
Lys (K)  19	  8.8%
Met (M)   3	  1.4%
Phe (F)   9	  4.1%
Pro (P)   9	  4.1%
Ser (S)  12	  5.5%
Thr (T)  11	  5.1%
Trp (W)   2	  0.9%
Tyr (Y)  13	  6.0%
Val (V)  12	  5.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 36

Atomic composition:

Carbon      C	      1119
Hydrogen    H	      1758
Nitrogen    N	       322
Oxygen      O	       319
Sulfur      S	         5

Formula: C1119H1758N322O319S5
Total number of atoms: 3523

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    30495
Abs 0.1% (=1 g/l)   1.220, assuming all pairs of Cys residues form cystines


Ext. coefficient    30370
Abs 0.1% (=1 g/l)   1.215, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.06
This classifies the protein as stable.



Aliphatic index: 72.86

Grand average of hydropathicity (GRAVY): -0.680