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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEAHNQFLKT FQKERHDMKE AEKDEILLME NSRRFVMFPI KYHEIWAAYK KVEASFWTAE

70 80 90 100 110 120
EIELAKDTED FQKLTDDQKT YIGNLLALSI SSDNLVNKYL IENFSAQLQN PEGKSFYGFQ

130 140 150 160 170 180
IMMENIYSEV YSMMVDAFFK DPKNIPLFKE IANLPEVKHK AAFIERWISN DDSLYAERLV

190 200 210 220 230 240
AFAAKEGIFQ AGNYASMFWL TDKKIMPGLA MANRNICRDR GAYTDFSCLL FAHLRTKPNP

250 260 270 280 290 300
KIIEKIITEA VEIEKEYYSN SLPVEKFGMD LKSIHTYIEF VADGLLQGFG NEKYYNAVNP

310 320 330 340
FEFMEDVATA GKTTFFEKKV SDYQKASDMS KSATPSKEIN FDDDF


References and documentation are available.

Number of amino acids: 345 Molecular weight: 40054.61 Theoretical pI: 5.11
Amino acid composition: 
Ala (A) 30 8.7% Arg (R) 9 2.6% Asn (N) 20 5.8% Asp (D) 22 6.4% Cys (C) 2 0.6% Gln (Q) 10 2.9% Glu (E) 33 9.6% Gly (G) 12 3.5% His (H) 6 1.7% Ile (I) 24 7.0% Leu (L) 24 7.0% Lys (K) 33 9.6% Met (M) 14 4.1% Phe (F) 27 7.8% Pro (P) 11 3.2% Ser (S) 21 6.1% Thr (T) 14 4.1% Trp (W) 4 1.2% Tyr (Y) 16 4.6% Val (V) 13 3.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 55 Total number of positively charged residues (Arg + Lys): 42 Atomic composition: Carbon C 1819 Hydrogen H 2763 Nitrogen N 451 Oxygen O 537 Sulfur S 16 Formula: C1819H2763N451O537S16 Total number of atoms: 5586 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 45965 Abs 0.1% (=1 g/l) 1.148, assuming all pairs of Cys residues form cystines Ext. coefficient 45840 Abs 0.1% (=1 g/l) 1.144, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 41.74 This classifies the protein as unstable. Aliphatic index: 73.88 Grand average of hydropathicity (GRAVY): -0.418