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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEDFDDDSFN DVLGAMEMPT AAKQPKVDAP AATAVNPAPS NSTEPSGSGR PAPGKPASNP

70 80 90 100 110 120
HCVLVHSKQR GNPILKSILN VPLEFRDDIV PDYVVGRTSC VLYLSLKYHN LNPDYICQRL

130 140 150 160 170 180
KALGKMYELR VLLVQVDTPE PNNALKSLTR ISLLADLTMM LAWNAEEAGK IIETYKQFEK

190 200 210 220 230 240
RPPDLIMERV ESNPHQKLLA ALTNIKPVNK TDAAALLHTF GNLGNIINAS EERLSQVMGL

250
GPRKAKKLYK TLQEPFLSK


References and documentation are available.

Number of amino acids: 259 Molecular weight: 28583.00 Theoretical pI: 8.32
Amino acid composition: 
Ala (A) 23 8.9% Arg (R) 11 4.2% Asn (N) 17 6.6% Asp (D) 14 5.4% Cys (C) 3 1.2% Gln (Q) 8 3.1% Glu (E) 15 5.8% Gly (G) 12 4.6% His (H) 5 1.9% Ile (I) 11 4.2% Leu (L) 32 12.4% Lys (K) 20 7.7% Met (M) 8 3.1% Phe (F) 6 2.3% Pro (P) 22 8.5% Ser (S) 16 6.2% Thr (T) 12 4.6% Trp (W) 1 0.4% Tyr (Y) 7 2.7% Val (V) 16 6.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 29 Total number of positively charged residues (Arg + Lys): 31 Atomic composition: Carbon C 1269 Hydrogen H 2050 Nitrogen N 348 Oxygen O 378 Sulfur S 11 Formula: C1269H2050N348O378S11 Total number of atoms: 4056 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 16055 Abs 0.1% (=1 g/l) 0.562, assuming all pairs of Cys residues form cystines Ext. coefficient 15930 Abs 0.1% (=1 g/l) 0.557, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.76 This classifies the protein as unstable. Aliphatic index: 91.54 Grand average of hydropathicity (GRAVY): -0.326