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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEDKRKRRAA TLSTALILFV ACCVYTLYIF KFDNPRLSPP VSLLPTISTL KKIEHVTDLN

70 80 90 100 110 120
KEYVFVGDVH GNYDEFIELI DDKIGGLGEN ITMILLGDFI HKGPDSDKVV SYILNHKDQV

130 140 150 160 170 180
KCVLGNHEIL VMMAYLNPDF SKWVRRPKLM TPLTFSTETN FIPQDISKIS NAHGRLAREL

190 200 210 220 230 240
GFSKLSQLAE HCSMAIELDL DITGDILFGA HAGMVPGDFM KPNQIPGVSS LSNMKYVDKK

250 260 270 280 290 300
NWSKTSREKE NKNYVRWYTL WDKYGDHFSN AKVFYGHDAS MGLNLRRQTK GLDTACIKNN

310 320
LLSSMKVKYD IKKGQYDYEL IQVQCS


References and documentation are available.

Number of amino acids: 326 Molecular weight: 37150.90 Theoretical pI: 8.55
Amino acid composition: 
Ala (A) 14 4.3% Arg (R) 12 3.7% Asn (N) 18 5.5% Asp (D) 24 7.4% Cys (C) 6 1.8% Gln (Q) 8 2.5% Glu (E) 14 4.3% Gly (G) 20 6.1% His (H) 10 3.1% Ile (I) 22 6.7% Leu (L) 34 10.4% Lys (K) 30 9.2% Met (M) 11 3.4% Phe (F) 14 4.3% Pro (P) 12 3.7% Ser (S) 23 7.1% Thr (T) 16 4.9% Trp (W) 4 1.2% Tyr (Y) 14 4.3% Val (V) 20 6.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 38 Total number of positively charged residues (Arg + Lys): 42 Atomic composition: Carbon C 1670 Hydrogen H 2624 Nitrogen N 442 Oxygen O 482 Sulfur S 17 Formula: C1670H2624N442O482S17 Total number of atoms: 5235 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 43235 Abs 0.1% (=1 g/l) 1.164, assuming all pairs of Cys residues form cystines Ext. coefficient 42860 Abs 0.1% (=1 g/l) 1.154, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.50 This classifies the protein as stable. Aliphatic index: 89.08 Grand average of hydropathicity (GRAVY): -0.286