ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEDSRLLITL ILVFGVIFLK KFFQSNQHPS AQRLSATGVN AHGRPQGSTQ NALRRTGRVN 

        70         80         90        100        110        120 
GGHPVTTQMV ETVQNLAPNL HPEQIRYSLE NTGSVEETVE RYLRGDEFSF PPGFEPSRAP 

       130        140        150        160        170        180 
MGANAAVDNN AAGGGEFNDP RKKNMICAEN LLDKFHVDLN EDMSNLSFKD LDIEERKRLL 

       190        200 
VWQARKNLET KLQSDKDLQS LLT 

References and documentation are available.

Number of amino acids: 203

Molecular weight: 22762.63

Theoretical pI: 6.22

Amino acid composition: 
Ala (A)  13	  6.4%
Arg (R)  14	  6.9%
Asn (N)  16	  7.9%
Asp (D)  11	  5.4%
Cys (C)   1	  0.5%
Gln (Q)  11	  5.4%
Glu (E)  15	  7.4%
Gly (G)  14	  6.9%
His (H)   5	  2.5%
Ile (I)   6	  3.0%
Leu (L)  23	 11.3%
Lys (K)  10	  4.9%
Met (M)   5	  2.5%
Phe (F)  10	  4.9%
Pro (P)  10	  4.9%
Ser (S)  13	  6.4%
Thr (T)  11	  5.4%
Trp (W)   1	  0.5%
Tyr (Y)   2	  1.0%
Val (V)  12	  5.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 26
Total number of positively charged residues (Arg + Lys): 24

Atomic composition:

Carbon      C	       993
Hydrogen    H	      1583
Nitrogen    N	       293
Oxygen      O	       309
Sulfur      S	         6

Formula: C993H1583N293O309S6
Total number of atoms: 3184

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     8480
Abs 0.1% (=1 g/l)   0.373, assuming all pairs of Cys residues form cystines


Ext. coefficient     8480
Abs 0.1% (=1 g/l)   0.373, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.44
This classifies the protein as unstable.



Aliphatic index: 79.26

Grand average of hydropathicity (GRAVY): -0.584