ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEEPYLDGIQ YNCVAPGKRF RPMDNLSGGE KTIAALALLF AVHGRNPAPF FVLDEIDAAL 

        70         80         90        100        110        120 
DNTNIGKVAS YICESAREHM QIIVISLKEE FYNKADSLIG IFPYPAACTT SGVLTFDLTR 

       130        140 
FKQIGLNEMT ENPPTPSIAT 

References and documentation are available.

Number of amino acids: 140

Molecular weight: 15373.61

Theoretical pI: 4.81

Amino acid composition: 
Ala (A)  14	 10.0%
Arg (R)   5	  3.6%
Asn (N)   8	  5.7%
Asp (D)   7	  5.0%
Cys (C)   3	  2.1%
Gln (Q)   3	  2.1%
Glu (E)  10	  7.1%
Gly (G)   9	  6.4%
His (H)   2	  1.4%
Ile (I)  12	  8.6%
Leu (L)  12	  8.6%
Lys (K)   6	  4.3%
Met (M)   4	  2.9%
Phe (F)   8	  5.7%
Pro (P)  10	  7.1%
Ser (S)   7	  5.0%
Thr (T)   9	  6.4%
Trp (W)   0	  0.0%
Tyr (Y)   5	  3.6%
Val (V)   6	  4.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 11

Atomic composition:

Carbon      C	       690
Hydrogen    H	      1076
Nitrogen    N	       176
Oxygen      O	       207
Sulfur      S	         7

Formula: C690H1076N176O207S7
Total number of atoms: 2156

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     7575
Abs 0.1% (=1 g/l)   0.493, assuming all pairs of Cys residues form cystines


Ext. coefficient     7450
Abs 0.1% (=1 g/l)   0.485, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 42.50
This classifies the protein as unstable.



Aliphatic index: 89.29

Grand average of hydropathicity (GRAVY): -0.006