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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEERKLLRAV KSTNPLVYLD ISIGKEDAGR MIIELRKDVV PKTAENFRAL CTGECGIGTL

70 80 90 100 110 120
GKPLHYKGTK FHKIKRVFVV QSGDVVKNDG SSGESIYGPV FDDENFELSH NEEGVVSMAN

130 140 150 160 170 180
YGKPNSNNSQ FFISAAGCEN LNGTNVVVGR VLRGLGIVAE MEQNCTDEGD PTAPIVIRDC

190 200 210 220 230 240
GEIAHNEDWG IECNDETTDK LPAYPQDWPR KLDKFTGDGA VELLTGIRQS GNHFYQLGRY

250 260 270 280 290 300
HEARAKYRKA NRYYHYLSRQ FGWQQLNPLK KHLVDEDLLK VDGFSVVNNI NAAAVDLKVG

310 320 330 340 350 360
NYTSAREVCN EAIRLDPKCS KAFYRRAQAQ RGLRNYEEAI NDLKTAHNLL PENKQILNEL

370 380
NSTKQLLAQY NRQQRNALKN LFA


References and documentation are available.

Number of amino acids: 383 Molecular weight: 43115.62 Theoretical pI: 7.58
Amino acid composition: 
Ala (A) 28 7.3% Arg (R) 24 6.3% Asn (N) 32 8.4% Asp (D) 22 5.7% Cys (C) 8 2.1% Gln (Q) 16 4.2% Glu (E) 28 7.3% Gly (G) 30 7.8% His (H) 9 2.3% Ile (I) 18 4.7% Leu (L) 35 9.1% Lys (K) 27 7.0% Met (M) 4 1.0% Phe (F) 13 3.4% Pro (P) 13 3.4% Ser (S) 17 4.4% Thr (T) 15 3.9% Trp (W) 3 0.8% Tyr (Y) 15 3.9% Val (V) 26 6.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 50 Total number of positively charged residues (Arg + Lys): 51 Atomic composition: Carbon C 1893 Hydrogen H 2989 Nitrogen N 551 Oxygen O 579 Sulfur S 12 Formula: C1893H2989N551O579S12 Total number of atoms: 6024 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 39350 Abs 0.1% (=1 g/l) 0.913, assuming all pairs of Cys residues form cystines Ext. coefficient 38850 Abs 0.1% (=1 g/l) 0.901, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.05 This classifies the protein as stable. Aliphatic index: 80.97 Grand average of hydropathicity (GRAVY): -0.592