ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEERMNVLHD FGIQSTRYLQ VNYEDSQDWF VLVSVIADLR NAFYVLFPIW FHIQETVGIN 

        70         80         90        100        110        120 
LLWVAVVGDW FNLVFKWILF GQRPYWWVLD TDYYSNSSVP LIKQFPVTCE TGPGSPSGHA 

       130        140        150        160        170        180 
MGTAGVYYVM VTSTLAIFRG KKKSTYGFRC LNVVLWLGYW AVQLNVCLSR IYLAAHFPHQ 

       190        200        210        220        230        240 
VVAGVLSGIA VAETFSHIRG IYNASLQRYC LITFFLFGFA LGFYLLLKGL GVDLLWTLEK 

       250        260        270        280        290        300 
AKRWCERPEW VHLDTTPFAS LFKNLGTLLG LGLALNSSMY RKSCKGELRK SLPFRLACIV 

       310        320        330        340        350 
ASLGLLHLFD SLKPPSQIES IFYILSFCKS ATVPFASVSL IPYCLARLLG QTHKKSL 

References and documentation are available.

Number of amino acids: 357

Molecular weight: 40555.57

Theoretical pI: 9.12

Amino acid composition: 
Ala (A)  22	  6.2%
Arg (R)  15	  4.2%
Asn (N)  11	  3.1%
Asp (D)  10	  2.8%
Cys (C)   9	  2.5%
Gln (Q)  11	  3.1%
Glu (E)  11	  3.1%
Gly (G)  25	  7.0%
His (H)   9	  2.5%
Ile (I)  18	  5.0%
Leu (L)  52	 14.6%
Lys (K)  16	  4.5%
Met (M)   5	  1.4%
Phe (F)  25	  7.0%
Pro (P)  14	  3.9%
Ser (S)  28	  7.8%
Thr (T)  17	  4.8%
Trp (W)  12	  3.4%
Tyr (Y)  17	  4.8%
Val (V)  30	  8.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 31

Atomic composition:

Carbon      C	      1904
Hydrogen    H	      2888
Nitrogen    N	       470
Oxygen      O	       484
Sulfur      S	        14

Formula: C1904H2888N470O484S14
Total number of atoms: 5760

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    91830
Abs 0.1% (=1 g/l)   2.264, assuming all pairs of Cys residues form cystines


Ext. coefficient    91330
Abs 0.1% (=1 g/l)   2.252, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.17
This classifies the protein as stable.



Aliphatic index: 107.00

Grand average of hydropathicity (GRAVY): 0.385