ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEGIKLNLCL LCIFTCDILG FSNGNIYNAH GSAYAGASAG AYKTLPNAYP YGTKHGPVYK 

        70         80         90        100        110        120 
PVKTSYHPTN SYPPTYGSKT NYLPLAKKLS SYKPIKTTYN AKTNYPPVYK PKMTYPPTYK 

       130        140        150        160        170        180 
PKPSYPPTYK PKPSYPATYK SKSSYPSSYK PKKTYPPTYK PKLTYPPTYK PKPSYPPTYK 

       190        200        210        220        230        240 
PKPSYPATYK SKSSYPPSYK TKKTYPSSYK PKKTYPSTYK PKVSYPPTYK SKKSYPPIYK 

       250        260        270        280        290        300 
TKASYPSSYK PKKTYPSTYK PKISYPPTYK AKPSYPTSYR AKPSYPSTYK AKPSYPPTYK 

       310        320        330        340        350        360 
AKPSYPPTYK AKPTYPSTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPSYK PKTTYPPSYK 

       370        380        390        400        410        420 
PKISYPPTYK AKPSYPPIYK AKPSYPPTYK AKPSYLPTYK AKPSYPPTYK AKPRYPTTYK 

       430        440        450        460        470        480 
AKPSYPPTYK AKPSYPPTYK AKLSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK 

       490        500        510        520        530        540 
TKPSYPRTYK AKPSYSSTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK 

       550        560        570        580        590        600 
AKPSYPPTYK AKPSYPQTYK AKSSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK 

       610        620        630        640        650        660 
AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPPTYK AKPSYPATYP 

       670        680        690        700        710        720 
STYKAKPSYP PTYKAKPSYP PTYKPKPSYP PTYKSKSSYP SSYKPKKTYP PTYKPKLTYP 

       730        740        750 
PIYKPKPSYP PTYKSSYPPR YKKKISYPSQ Y 

References and documentation are available.

Number of amino acids: 751

Molecular weight: 85791.18

Theoretical pI: 9.99

Amino acid composition: 
Ala (A)  51	  6.8%
Arg (R)   4	  0.5%
Asn (N)   9	  1.2%
Asp (D)   1	  0.1%
Cys (C)   3	  0.4%
Gln (Q)   2	  0.3%
Glu (E)   1	  0.1%
Gly (G)   9	  1.2%
His (H)   3	  0.4%
Ile (I)  11	  1.5%
Leu (L)  13	  1.7%
Lys (K) 144	 19.2%
Met (M)   2	  0.3%
Phe (F)   2	  0.3%
Pro (P) 181	 24.1%
Ser (S)  90	 12.0%
Thr (T)  78	 10.4%
Trp (W)   0	  0.0%
Tyr (Y) 143	 19.0%
Val (V)   4	  0.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 2
Total number of positively charged residues (Arg + Lys): 148

Atomic composition:

Carbon      C	      4107
Hydrogen    H	      6064
Nitrogen    N	       924
Oxygen      O	      1078
Sulfur      S	         5

Formula: C4107H6064N924O1078S5
Total number of atoms: 12178

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   213195
Abs 0.1% (=1 g/l)   2.485, assuming all pairs of Cys residues form cystines


Ext. coefficient   213070
Abs 0.1% (=1 g/l)   2.484, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 44.31
This classifies the protein as unstable.



Aliphatic index: 20.80

Grand average of hydropathicity (GRAVY): -1.353