ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEGKFAISES TNLLQRIKDF TQSVVVDLAE GRSPKISINQ FRNYCMNPEA DCLCSSDKPK 

        70         80         90        100        110        120 
GQEIFTLKKE PQTYRIDMLL RVLLIVQQLL QENRHASKRD IYYMHPSAFK AQSIVDRAIG 

       130        140        150        160        170        180 
DICILFQCSR YNLNVVSVGN GLVMGWLKFR EAGRKFDCLN SLNTAYPVPV LVEEVEDIVS 

       190        200        210        220        230        240 
LAEYILVVEK ETVFQRLAND MFCKTNRCIV ITGRGYPDVS TRRFLRLLME KLHLPVHCLV 

       250        260        270        280        290        300 
DCDPYGFEIL ATYRFGSMQM AYDIESLRAP DMKWLGAFPS DSEVYSVPKQ CLLPLTEEDK 

       310        320        330        340        350        360 
KRTEAMLLRC YLKREMPQWR LELETMLKRG VKFEIEALSV HSLSFLSEVY IPSKIRREVS 


SP 

References and documentation are available.

Number of amino acids: 362

Molecular weight: 41803.71

Theoretical pI: 7.91

Amino acid composition: 
Ala (A)  17	  4.7%
Arg (R)  26	  7.2%
Asn (N)  12	  3.3%
Asp (D)  18	  5.0%
Cys (C)  12	  3.3%
Gln (Q)  14	  3.9%
Glu (E)  28	  7.7%
Gly (G)  14	  3.9%
His (H)   5	  1.4%
Ile (I)  21	  5.8%
Leu (L)  42	 11.6%
Lys (K)  22	  6.1%
Met (M)  13	  3.6%
Phe (F)  16	  4.4%
Pro (P)  17	  4.7%
Ser (S)  27	  7.5%
Thr (T)  13	  3.6%
Trp (W)   3	  0.8%
Tyr (Y)  14	  3.9%
Val (V)  28	  7.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 46
Total number of positively charged residues (Arg + Lys): 48

Atomic composition:

Carbon      C	      1867
Hydrogen    H	      2977
Nitrogen    N	       501
Oxygen      O	       535
Sulfur      S	        25

Formula: C1867H2977N501O535S25
Total number of atoms: 5905

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    38110
Abs 0.1% (=1 g/l)   0.912, assuming all pairs of Cys residues form cystines


Ext. coefficient    37360
Abs 0.1% (=1 g/l)   0.894, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 50.44
This classifies the protein as unstable.



Aliphatic index: 95.00

Grand average of hydropathicity (GRAVY): -0.148