ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEGMNMGSSM NMDAMSSASK TVASSMASMS MDAMSSASKT ILSSMSSMSM EAMSSASKTL 

        70         80         90        100        110        120 
ASTMSSMASM SMGSSSMSGM SMSMSSTPTS SASAQTTSDS SMSGMSGMSS SDNSSSSGMD 

       130        140        150        160        170        180 
MDMSMGMNYY LTPTYKNYPV LFHHLHANNS GKAFGIFLLF VVAAFVYKLL LFVSWCLEVH 

       190        200        210        220        230        240 
WFKKWDKQNK YSTLPSANSK DEGKHYDTEN NFEIQGLPKL PNLLSDIFVP SLMDLFHDII 

       250        260        270        280        290        300 
RAFLVFTSTM IIYMLMLATM SFVLTYVFAV ITGLALSEVF FNRCKIAMLK RWDIQREIQK 

       310        320        330        340        350        360 
AKSCPGFGNC QCGRHPEPSP DPIAVADTTS GSDQSTRLEK NNESKVAISE NNQKKTPTQE 

       370        380        390        400 
EGCNCATDSG KNQANIERDI LENSKLQEQS GNMDQNLLPA EKFTHN 

References and documentation are available.

Number of amino acids: 406

Molecular weight: 44441.60

Theoretical pI: 5.78

Amino acid composition: 
Ala (A)  29	  7.1%
Arg (R)   7	  1.7%
Asn (N)  25	  6.2%
Asp (D)  19	  4.7%
Cys (C)   7	  1.7%
Gln (Q)  13	  3.2%
Glu (E)  18	  4.4%
Gly (G)  20	  4.9%
His (H)   8	  2.0%
Ile (I)  16	  3.9%
Leu (L)  30	  7.4%
Lys (K)  24	  5.9%
Met (M)  37	  9.1%
Phe (F)  18	  4.4%
Pro (P)  14	  3.4%
Ser (S)  69	 17.0%
Thr (T)  24	  5.9%
Trp (W)   4	  1.0%
Tyr (Y)   9	  2.2%
Val (V)  15	  3.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 37
Total number of positively charged residues (Arg + Lys): 31

Atomic composition:

Carbon      C	      1909
Hydrogen    H	      3013
Nitrogen    N	       509
Oxygen      O	       621
Sulfur      S	        44

Formula: C1909H3013N509O621S44
Total number of atoms: 6096

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    35785
Abs 0.1% (=1 g/l)   0.805, assuming all pairs of Cys residues form cystines


Ext. coefficient    35410
Abs 0.1% (=1 g/l)   0.797, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 59.70
This classifies the protein as unstable.



Aliphatic index: 62.04

Grand average of hydropathicity (GRAVY): -0.225