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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEGSSSTIAR KTWELENSIL TVDSPDSTSD NIFYYDDTSQ TRFQQEKPWE NDPHYFKRVK

70 80 90 100 110 120
ISALALLKMV VHARSGGTIE IMGLMQGKTD GDTIIVMDAF ALPVEGTETR VNAQDDAYEY

130 140 150 160 170 180
MVEYSQTNKL AGRLENVVGW YHSHPGYGCW LSGIDVSTQR LNQQHQEPFL AVVIDPTRTV

190 200 210 220 230 240
SAGKVEIGAF RTYSKGYKPP DEPVSEYQTI PLNKIEDFGV HCKQYYSLDV TYFKSSLDSH

250 260 270 280 290 300
LLDLLWNKYW VNTLSSSPLL GNGDYVAGQI SDLAEKLEQA ESHLVQSRFG GVVPSSLHKK

310 320 330 340 350
KEDESQLTKI TRDSAKITVE QVHGLMSQVI KDELFNSMRQ SNNKSPTDSS DPDPMITY


References and documentation are available.

Number of amino acids: 358 Molecular weight: 40318.08 Theoretical pI: 5.11
Amino acid composition: 
Ala (A) 16 4.5% Arg (R) 12 3.4% Asn (N) 14 3.9% Asp (D) 26 7.3% Cys (C) 2 0.6% Gln (Q) 19 5.3% Glu (E) 23 6.4% Gly (G) 22 6.1% His (H) 10 2.8% Ile (I) 18 5.0% Leu (L) 29 8.1% Lys (K) 22 6.1% Met (M) 9 2.5% Phe (F) 10 2.8% Pro (P) 16 4.5% Ser (S) 37 10.3% Thr (T) 24 6.7% Trp (W) 6 1.7% Tyr (Y) 17 4.7% Val (V) 26 7.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 34 Atomic composition: Carbon C 1785 Hydrogen H 2763 Nitrogen N 475 Oxygen O 568 Sulfur S 11 Formula: C1785H2763N475O568S11 Total number of atoms: 5602 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 58455 Abs 0.1% (=1 g/l) 1.450, assuming all pairs of Cys residues form cystines Ext. coefficient 58330 Abs 0.1% (=1 g/l) 1.447, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.93 This classifies the protein as unstable. Aliphatic index: 76.73 Grand average of hydropathicity (GRAVY): -0.525