ProtParam
User-provided sequence:
10 20 30 40 50 60
MEHGSFTNVS HASFTLSEED HTLANAVRFV LNQDPRVTVA AYTIPHPSLE QVNIRVQTTG
70 80 90 100 110 120
DPAREVFKDA CQELMQMNRH VRSVFDKAVA EYKDEQKRKE EAEEEELKRQ RDLFGSMDIE
NN
References and
documentation are available.
Number of amino acids: 122
Molecular weight: 14078.60
Theoretical pI: 5.08
Total number of negatively charged residues (Asp + Glu): 23
Total number of positively charged residues (Arg + Lys): 15
Atomic composition:
Carbon C 605
Hydrogen H 953
Nitrogen N 179
Oxygen O 199
Sulfur S 5
Formula: C
605H
953N
179O
199S
5
Total number of atoms: 1941
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 2980
Abs 0.1% (=1 g/l) 0.212, assuming all pairs of Cys residues form cystines
Ext. coefficient 2980
Abs 0.1% (=1 g/l) 0.212, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 48.24
This classifies the protein as unstable.
Aliphatic index: 66.31
Grand average of hydropathicity (GRAVY): -0.811