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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEISGKMHEG DSLVVSPKSL DELPINVIFQ ILSELKFSDL KNVSATCWTL RILTNEKLMY

70 80 90 100 110 120
YSILHDPKNQ YLWTKRYFLD SLRMLQRNRR GFDFVSLNDT TFFQSLRYLH NGVRKVSGNL

130 140 150 160 170 180
LRLLESNDDL GINEIDTASE SEDNDNMNND ENDNESNGYD SQNQRVGKKY INDGRTDGEM

190 200 210 220 230 240
MPDNSDLWET EDESDIDTTN DVNGLDQIYA ENISVFEEDT GSDSYNDGQI QPVQISMNDF

250 260 270 280 290 300
ADSESTPTKK PRTKPTKIDK EGLKYLRVLE GFHRIGVISG RETPDRIITH NTSATPNKYG

310 320 330 340 350 360
NLLDDVQFTP LSTISSLLKR IDSGSDSNHA HSPDSFGISH SRSGSSVFSD GAPKLADQPW

370 380 390 400 410 420
SKIYELDHQS LSSSDSDSSS STEFIRQLQS SKKVKDKAVL FERLLAKSKE RSVSLKEKKS

430 440 450 460 470 480
HASSNNGNCR KVSDDYLAET RRNASPAPSS VSSIDTEMRL TMQEVKNNSN DHFDSHAKTK

490 500 510
SSSTHGIKHS KIHHRKKLKA LVMDGNRICY EKITE


References and documentation are available.

Number of amino acids: 515 Molecular weight: 58166.26 Theoretical pI: 5.65
Amino acid composition: 
Ala (A) 16 3.1% Arg (R) 27 5.2% Asn (N) 37 7.2% Asp (D) 48 9.3% Cys (C) 3 0.6% Gln (Q) 16 3.1% Glu (E) 32 6.2% Gly (G) 25 4.9% His (H) 16 3.1% Ile (I) 29 5.6% Leu (L) 44 8.5% Lys (K) 39 7.6% Met (M) 11 2.1% Phe (F) 16 3.1% Pro (P) 16 3.1% Ser (S) 71 13.8% Thr (T) 29 5.6% Trp (W) 4 0.8% Tyr (Y) 14 2.7% Val (V) 22 4.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 80 Total number of positively charged residues (Arg + Lys): 66 Atomic composition: Carbon C 2505 Hydrogen H 3970 Nitrogen N 724 Oxygen O 843 Sulfur S 14 Formula: C2505H3970N724O843S14 Total number of atoms: 8056 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 42985 Abs 0.1% (=1 g/l) 0.739, assuming all pairs of Cys residues form cystines Ext. coefficient 42860 Abs 0.1% (=1 g/l) 0.737, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.98 This classifies the protein as unstable. Aliphatic index: 70.78 Grand average of hydropathicity (GRAVY): -0.840