ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEKKKILDAA LAPRIISGVP TDGQPLSGGP LSWAWCHTTL KRWALMKTRP YKYPLSTEPP 

        70         80         90        100        110 
TPPSVPNSAS VNHNTTTNTT LSYTRCHSTT YTKPLRERSS RPWTRSATIS RLPPRSWTN 

References and documentation are available.

Number of amino acids: 119

Molecular weight: 13360.26

Theoretical pI: 10.58

Amino acid composition: 
Ala (A)   7	  5.9%
Arg (R)  10	  8.4%
Asn (N)   5	  4.2%
Asp (D)   2	  1.7%
Cys (C)   2	  1.7%
Gln (Q)   1	  0.8%
Glu (E)   3	  2.5%
Gly (G)   4	  3.4%
His (H)   3	  2.5%
Ile (I)   4	  3.4%
Leu (L)  10	  8.4%
Lys (K)   7	  5.9%
Met (M)   2	  1.7%
Phe (F)   0	  0.0%
Pro (P)  15	 12.6%
Ser (S)  14	 11.8%
Thr (T)  18	 15.1%
Trp (W)   5	  4.2%
Tyr (Y)   4	  3.4%
Val (V)   3	  2.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 5
Total number of positively charged residues (Arg + Lys): 17

Atomic composition:

Carbon      C	       592
Hydrogen    H	       939
Nitrogen    N	       173
Oxygen      O	       172
Sulfur      S	         4

Formula: C592H939N173O172S4
Total number of atoms: 1880

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    33585
Abs 0.1% (=1 g/l)   2.514, assuming all pairs of Cys residues form cystines


Ext. coefficient    33460
Abs 0.1% (=1 g/l)   2.504, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 52.59
This classifies the protein as unstable.



Aliphatic index: 59.08

Grand average of hydropathicity (GRAVY): -0.752