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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEKKVICQDI FWSCDGTSFV SVHNDFGIRQ YLVPEESNTD KLNRNLLLPF TRFFRNQSIV

70 80 90 100 110 120
SCAIDPFYTL YNENSDRLAG DRIVVGGKNF PLQLYSLMDG QCILSYDTMN KINGEYETVY

130 140 150 160 170 180
SVKIDVESRV YTGSCRNKVA IYDKSRRDAV WMNQSTKKAS KGRQSIISCF EEQPMGGQAL

190 200 210 220 230 240
SRGSLLCGSY ANEMFQVDCR HQRLERLNYT RTVAGGIVQI LTSDNGRYVY VVRRNSDAIS

250 260 270 280 290 300
IYDRRNLQHE LNVLRLPFRI HHNSAKLKAY IDTAYGLSMG TPQGTILNWG RDLVEFGGVP

310 320 330 340 350
SHNSVEDPLI TSIPPESEWR TNLDSTIPAT VVKNCPGDPE LFALSHGGTI SLCRFGG


References and documentation are available.

Number of amino acids: 357 Molecular weight: 40307.63 Theoretical pI: 7.98
Amino acid composition: 
Ala (A) 14 3.9% Arg (R) 26 7.3% Asn (N) 23 6.4% Asp (D) 21 5.9% Cys (C) 10 2.8% Gln (Q) 14 3.9% Glu (E) 17 4.8% Gly (G) 27 7.6% His (H) 7 2.0% Ile (I) 23 6.4% Leu (L) 30 8.4% Lys (K) 14 3.9% Met (M) 7 2.0% Phe (F) 14 3.9% Pro (P) 14 3.9% Ser (S) 32 9.0% Thr (T) 19 5.3% Trp (W) 4 1.1% Tyr (Y) 16 4.5% Val (V) 25 7.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 38 Total number of positively charged residues (Arg + Lys): 40 Atomic composition: Carbon C 1773 Hydrogen H 2778 Nitrogen N 504 Oxygen O 538 Sulfur S 17 Formula: C1773H2778N504O538S17 Total number of atoms: 5610 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 46465 Abs 0.1% (=1 g/l) 1.153, assuming all pairs of Cys residues form cystines Ext. coefficient 45840 Abs 0.1% (=1 g/l) 1.137, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 41.85 This classifies the protein as unstable. Aliphatic index: 82.13 Grand average of hydropathicity (GRAVY): -0.358