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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEKNTAPFVV DTAPTTPPDK LVAPSIEEVN SNPNELRALR GQGRYFGVSD DDKDAIKEAA

70 80 90 100 110 120
PKCNNCSQRG HLKKDCPHII CSYCGATDDH YSRHCPKAIQ CSKCDEVGHY RSQCPHKWKK

130 140 150 160 170 180
VQCTLCKSKK HSKERCPSIW RAYILVDDNE KAKPKVLPFH TIYCYNCGGK GHFGDDCKEK

190 200 210 220 230 240
RSSRVPNEDG SAFTGSNLSV ELKQEYYRHM NRNSDENEDY QFSESIYDED PLPRPSHKRH

250 260 270 280 290 300
SQNDHSHSGR NKRRASNFHP PPYQKSNVIQ PTIRGETLSL NNNISKNSRY QNTKVNVSSI

310 320 330 340
SENMYGSRYN PSTYVDNNSI SNSSNYRNYN SYQPYRSGTL GKRR


References and documentation are available.

Number of amino acids: 344 Molecular weight: 39343.55 Theoretical pI: 9.06
Amino acid composition: 
Ala (A) 13 3.8% Arg (R) 24 7.0% Asn (N) 31 9.0% Asp (D) 21 6.1% Cys (C) 15 4.4% Gln (Q) 12 3.5% Glu (E) 18 5.2% Gly (G) 17 4.9% His (H) 15 4.4% Ile (I) 14 4.1% Leu (L) 13 3.8% Lys (K) 29 8.4% Met (M) 3 0.9% Phe (F) 7 2.0% Pro (P) 23 6.7% Ser (S) 39 11.3% Thr (T) 13 3.8% Trp (W) 2 0.6% Tyr (Y) 20 5.8% Val (V) 15 4.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 39 Total number of positively charged residues (Arg + Lys): 53 Atomic composition: Carbon C 1685 Hydrogen H 2616 Nitrogen N 520 Oxygen O 538 Sulfur S 18 Formula: C1685H2616N520O538S18 Total number of atoms: 5377 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41675 Abs 0.1% (=1 g/l) 1.059, assuming all pairs of Cys residues form cystines Ext. coefficient 40800 Abs 0.1% (=1 g/l) 1.037, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.51 This classifies the protein as unstable. Aliphatic index: 47.03 Grand average of hydropathicity (GRAVY): -1.181