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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEKPNPRRPS NSVLPYETPR LRDHYLLGKK LGQGQFGTTY LCTEKSSSAN YACKSIPKRK

70 80 90 100 110 120
LVCREDYEDV WREIQIMHHL SEHPNVVRIK GTYEDSVFVH IVMEVCEGGE LFDRIVSKGC

130 140 150 160 170 180
FSEREAAKLI KTILGVVEAC HSLGVMHRDL KPENFLFDSP SDDAKLKATD FGLSVFYKPG

190 200 210 220 230 240
QYLYDVVGSP YYVAPEVLKK CYGPEIDVWS AGVILYILLS GVPPFWAETE SGIFRQILQG

250 260 270 280 290 300
KIDFKSDPWP TISEGAKDLI YKMLDRSPKK RISAHEALCH PWIVDEHAAP DKPLDPAVLS

310 320 330 340 350 360
RLKQFSQMNK IKKMALRVIA ERLSEEEIGG LKELFKMIDT DNSGTITFEE LKAGLKRVGS

370 380 390 400 410 420
ELMESEIKSL MDAADIDNSG TIDYGEFLAA TLHINKMERE ENLVVAFSYF DKDGSGYITI

430 440 450 460 470 480
DELQQACTEF GLCDTPLDDM IKEIDLDNDG KIDFSEFTAM MKKGDGVGRS RTMRNNLNFN

490 500
IAEAFGVEDT SSTAKSDDSP K


References and documentation are available.

Number of amino acids: 501 Molecular weight: 56416.37 Theoretical pI: 5.22
Amino acid composition: 
Ala (A) 29 5.8% Arg (R) 22 4.4% Asn (N) 15 3.0% Asp (D) 39 7.8% Cys (C) 10 2.0% Gln (Q) 10 2.0% Glu (E) 42 8.4% Gly (G) 34 6.8% His (H) 11 2.2% Ile (I) 33 6.6% Leu (L) 44 8.8% Lys (K) 41 8.2% Met (M) 15 3.0% Phe (F) 22 4.4% Pro (P) 24 4.8% Ser (S) 38 7.6% Thr (T) 21 4.2% Trp (W) 5 1.0% Tyr (Y) 17 3.4% Val (V) 29 5.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 81 Total number of positively charged residues (Arg + Lys): 63 Atomic composition: Carbon C 2511 Hydrogen H 3940 Nitrogen N 660 Oxygen O 765 Sulfur S 25 Formula: C2511H3940N660O765S25 Total number of atoms: 7901 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 53455 Abs 0.1% (=1 g/l) 0.948, assuming all pairs of Cys residues form cystines Ext. coefficient 52830 Abs 0.1% (=1 g/l) 0.936, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 46.96 This classifies the protein as unstable. Aliphatic index: 82.51 Grand average of hydropathicity (GRAVY): -0.367