ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MELDECLERL YKAQLLPEVT VRALCFKLKE MLVKESNVIH IQTPVTVVGD MHGQFHDMLE 

        70         80         90        100        110        120 
IFQIGGPVPD TNYLFLGDYV DRGLYSVETI MLLIVLKLRY PSRIHLLRGN HESRQITQSY 

       130        140        150        160        170        180 
GFYTECLNKY GGNSRVWQYL TDIFDYLVLC CIIDDEIFCV HGGLSPNVQT IDQIKIIDRF 

       190        200        210        220        230        240 
REIPHDGAMA DLVWSDPEEN NNPTLDHPDN SGQHFQVSPR GAGYTFGRSV VEKFLRMNDM 

       250        260        270        280        290        300 
NRIYRAHQLC NEGYQIYFDG LVTTVWSAPN YCYRCGNKAS ILELYSKDQF YFNVFEEAPE 

       310        320        330        340        350        360 
NKLLKENSMN DNALEDSISN PVANRKLIAD YFEDDSASAD GSTDPEMYIF SDVYQARSAS 


NRHVDYFL 

References and documentation are available.

Number of amino acids: 368

Molecular weight: 42432.88

Theoretical pI: 4.85

Amino acid composition: 
Ala (A)  16	  4.3%
Arg (R)  19	  5.2%
Asn (N)  23	  6.2%
Asp (D)  29	  7.9%
Cys (C)   9	  2.4%
Gln (Q)  15	  4.1%
Glu (E)  24	  6.5%
Gly (G)  21	  5.7%
His (H)  11	  3.0%
Ile (I)  23	  6.2%
Leu (L)  35	  9.5%
Lys (K)  13	  3.5%
Met (M)  10	  2.7%
Phe (F)  18	  4.9%
Pro (P)  15	  4.1%
Ser (S)  23	  6.2%
Thr (T)  14	  3.8%
Trp (W)   3	  0.8%
Tyr (Y)  22	  6.0%
Val (V)  25	  6.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 53
Total number of positively charged residues (Arg + Lys): 32

Atomic composition:

Carbon      C	      1894
Hydrogen    H	      2883
Nitrogen    N	       501
Oxygen      O	       572
Sulfur      S	        19

Formula: C1894H2883N501O572S19
Total number of atoms: 5869

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    49780
Abs 0.1% (=1 g/l)   1.173, assuming all pairs of Cys residues form cystines


Ext. coefficient    49280
Abs 0.1% (=1 g/l)   1.161, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.37
This classifies the protein as stable.



Aliphatic index: 85.52

Grand average of hydropathicity (GRAVY): -0.325