ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MELNDPSIIS SSQFSGELSD SDTAAATHKS QQAISNLFQK LAKKGREEKP IGSVESSTDS 

        70         80         90        100        110        120 
SNISVATSGN NKESNKKKNK KTAMLNFSSL TDPITNYKPM DLQYKTYAYS MNELYHLKPS 

       130        140        150        160        170        180 
LASASYEEDP LISELVRSLP KRKFWRLRMG PPDQKHANNH HFNGNNGGGS WKAGYKNGKN 

       190        200        210        220        230        240 
DERRMSRTKN MQGGKRRSQQ DDEEKKIDQE MLEMDKNLQL GGDVGHSIAD FEDWKAKMKE 

       250        260        270        280        290        300 
LELKKLSKSK GISNSTAIAP RESASHETPT DLRPVIPRGP SSITDFLNLK RQDKKEESSQ 

       310        320        330        340        350        360 
QTPGIPVGQP SLSKTSIEQV NELETNSDLG KSSSSRFSSF FNKSATSLPS LDNNNQVPSS 

       370        380        390        400        410        420 
NVSVVNNDGN STPHQSGSRL MSFFKESRSS TPNAESQLLS ASDKDNGKMQ TLPQFQQQPQ 

       430        440        450        460        470        480 
QMQPMAFTQH PPNNNAFFNG LLNKGKSETS TPPPPPPGLI AHQGPQFPVM GVPPNFPQRM 

       490        500        510        520        530        540 
MPPPPGLVQF QKDSKDVNKK EDRQLRQNKN PNGTRNSKGK QEETATPDLP QQQYMPPPPP 

       550        560        570        580        590        600 
PGFFPMHPNF PNGPMPPLPQ GFPIPPNGML PVTGQQPQPP YPNMMLQGNF PPNFQQGFGS 

       610        620        630 
NSPMPIPSII NANGKNVTNQ LPPGLNSKKN IK 

References and documentation are available.

Number of amino acids: 632

Molecular weight: 69762.12

Theoretical pI: 9.49

Amino acid composition: 
Ala (A)  25	  4.0%
Arg (R)  21	  3.3%
Asn (N)  57	  9.0%
Asp (D)  28	  4.4%
Cys (C)   0	  0.0%
Gln (Q)  47	  7.4%
Glu (E)  31	  4.9%
Gly (G)  42	  6.6%
His (H)  11	  1.7%
Ile (I)  21	  3.3%
Leu (L)  43	  6.8%
Lys (K)  54	  8.5%
Met (M)  24	  3.8%
Phe (F)  26	  4.1%
Pro (P)  72	 11.4%
Ser (S)  73	 11.6%
Thr (T)  28	  4.4%
Trp (W)   3	  0.5%
Tyr (Y)   9	  1.4%
Val (V)  17	  2.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 59
Total number of positively charged residues (Arg + Lys): 75

Atomic composition:

Carbon      C	      3033
Hydrogen    H	      4788
Nitrogen    N	       878
Oxygen      O	       965
Sulfur      S	        24

Formula: C3033H4788N878O965S24
Total number of atoms: 9688

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    29910
Abs 0.1% (=1 g/l)   0.429

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 57.35
This classifies the protein as unstable.



Aliphatic index: 51.25

Grand average of hydropathicity (GRAVY): -1.017