ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MELTSFHRSS LLFLISLTLI ILPTTTTSIG VNYGQIGDNL PSPTDVIPLI KSIGATKVKL 

        70         80         90        100        110        120 
YDANPQILKA FSNTGIEFII GLGNEYLSKM KDPSKALTWI KQNVTPFLPA TNITCITIGN 

       130        140        150        160        170        180 
EILALNDSSL TTNLLPAMQG VHSALITAGL SDQISVTTAH SLSILKSSFP PSAGEFQPDL 

       190        200        210        220        230        240 
LDSLTPILEF HRKTDSPFLI NAYPFFAYKG NPKEVPLDFV LFQPNQGIVD PATGFHYDNM 

       250        260        270        280        290        300 
LFAQIDAVYS ALAAAGFKSL RVEISETGWP SKGDDDEVGA TPENAKRYNG NLIKMMMSGK 

       310        320        330        340        350        360 
KTKTPLKPNN DLSIYVFALF NENLKPGPTS ERNYGLFKPD GTQAYSLGFA LNDVVRGASG 

       370        380        390        400        410        420 
GGTGGGNSSS GGGRDKSPVF PVSPVAPDSA STGYLAISAS PVTGKRKGKG AILSLVVSML 


LARHLL 

References and documentation are available.

Number of amino acids: 426

Molecular weight: 45421.03

Theoretical pI: 7.75

Amino acid composition: 
Ala (A)  32	  7.5%
Arg (R)   9	  2.1%
Asn (N)  24	  5.6%
Asp (D)  21	  4.9%
Cys (C)   1	  0.2%
Gln (Q)  10	  2.3%
Glu (E)  13	  3.1%
Gly (G)  38	  8.9%
His (H)   6	  1.4%
Ile (I)  29	  6.8%
Leu (L)  49	 11.5%
Lys (K)  26	  6.1%
Met (M)   8	  1.9%
Phe (F)  21	  4.9%
Pro (P)  31	  7.3%
Ser (S)  42	  9.9%
Thr (T)  31	  7.3%
Trp (W)   2	  0.5%
Tyr (Y)  12	  2.8%
Val (V)  21	  4.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 34
Total number of positively charged residues (Arg + Lys): 35

Atomic composition:

Carbon      C	      2053
Hydrogen    H	      3243
Nitrogen    N	       527
Oxygen      O	       614
Sulfur      S	         9

Formula: C2053H3243N527O614S9
Total number of atoms: 6446

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    28880
Abs 0.1% (=1 g/l)   0.636, assuming all pairs of Cys residues form cystines


Ext. coefficient    28880
Abs 0.1% (=1 g/l)   0.636, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.74
This classifies the protein as stable.



Aliphatic index: 93.22

Grand average of hydropathicity (GRAVY): 0.006