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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MELWTEARAL KASLRGESTI SLKHHQVIVS EDLSRTSSLP EDFSVECFLD FSEGQKEEEE

70 80 90 100 110 120
EVVSVSSSQE QEEQEHDCVF SSQPCIFDQL PSLPDEDVEE LEWVSRVVDD CSSPEVSLLL

130 140 150 160 170 180
TQTHKTKPSF SRIPVKPRTK RSRNSLTGSR VWPLVSTNHQ HAATEQLRKK KQETVLVFQR

190 200 210 220 230 240
RCSHCGTNNT PQWRTGPVGP KTLCNACGVR FKSGRLCPEY RPADSPTFSN EIHSNLHRKV

250 260
LELRKSKELG EETGEASTKS DPVKFGSKW


References and documentation are available.

Number of amino acids: 269 Molecular weight: 30468.05 Theoretical pI: 6.03
Amino acid composition: 
Ala (A) 8 3.0% Arg (R) 18 6.7% Asn (N) 7 2.6% Asp (D) 11 4.1% Cys (C) 9 3.3% Gln (Q) 13 4.8% Glu (E) 30 11.2% Gly (G) 11 4.1% His (H) 9 3.3% Ile (I) 5 1.9% Leu (L) 23 8.6% Lys (K) 18 6.7% Met (M) 1 0.4% Phe (F) 10 3.7% Pro (P) 16 5.9% Ser (S) 35 13.0% Thr (T) 18 6.7% Trp (W) 5 1.9% Tyr (Y) 1 0.4% Val (V) 21 7.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 41 Total number of positively charged residues (Arg + Lys): 36 Atomic composition: Carbon C 1319 Hydrogen H 2094 Nitrogen N 384 Oxygen O 426 Sulfur S 10 Formula: C1319H2094N384O426S10 Total number of atoms: 4233 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 29490 Abs 0.1% (=1 g/l) 0.968, assuming all pairs of Cys residues form cystines Ext. coefficient 28990 Abs 0.1% (=1 g/l) 0.951, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 56.26 This classifies the protein as unstable. Aliphatic index: 66.21 Grand average of hydropathicity (GRAVY): -0.762