ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEMNMDMDMD MELASIVSSL SALSHSNNNG GQAAAAGIVN GGAAGSQQIG GFRRSSFTTA 

        70         80         90        100        110        120 
NEVDSEILLL HGSSESSPIF KKTALSVGTA PPFSTNSKKF FGNGGNYYQY RSTDTASLSS 

       130        140        150        160        170        180 
ASYNNYHTHH TAANLGKNNK VNHLLGQYSA SIAGPVYYNG NDNNNSGGEG FFEKFGKSLI 

       190        200        210        220        230        240 
DGTRELESQD RPDAVNTQSQ FISKSVSNAS LDTQNTFEQN VESDKNFNKL NRNTTNSGSL 

       250        260        270        280        290        300 
YHSSSNSGSS ASLESENAHY PKRNIWNVAN TPVFRPSNNP AAVGATNVAL PNQQDGPANN 

       310        320        330        340        350        360 
NFPPYMNGFP PNQFHQGPHY QNFPNYLIGS PSNFISQMIS VQIPANEDTE DSNGKKKKKA 

       370        380        390        400        410        420 
NRPSSVSSPS SPPNNSPFPF AYPNPMMFMP PPPLSAPQQQ QQQQQQQQQE DQQQQQQQEN 

       430        440        450        460        470        480 
PYIYYPTPNP IPVKMPKDEK TFKKRNNKNH PANNSNNANK QANPYLENSI PTKNTSKKNA 

       490        500        510        520        530        540 
SSKSNESTAN NHKSHSHSHP HSQSLQQQQQ TYHRSPLLEQ LRNSSSDKNS NSNMSLKDIF 

       550        560        570        580        590        600 
GHSLEFCKDQ HGSRFIQREL ATSPASEKEV IFNEIRDDAI ELSNDVFGNY VIQKFFEFGS 

       610        620        630        640        650        660 
KIQKNTLVDQ FKGNMKQLSL QMYACRVIQK ALEYIDSNQR IELVLELSDS VLQMIKDQNG 

       670        680        690        700        710        720 
NHVIQKAIET IPIEKLPFIL SSLTGHIYHL STHSYGCRVI QRLLEFGSSE DQESILNELK 

       730        740        750        760        770        780 
DFIPYLIQDQ YGNYVIQYVL QQDQFTNKEM VDIKQEIIET VANNVVEYSK HKFASNVVEK 

       790        800        810        820        830        840 
SILYGSKNQK DLIISKILPR DKNHALNLED DSPMILMIKD QFANYVIQKL VNVSEGEGKK 

       850        860        870 
LIVIAIRAYL DKLNKSNSLG NRHLASVEKL AALVENAEV 

References and documentation are available.

Number of amino acids: 879

Molecular weight: 98067.78

Theoretical pI: 6.71

Amino acid composition: 
Ala (A)  52	  5.9%
Arg (R)  22	  2.5%
Asn (N)  96	 10.9%
Asp (D)  37	  4.2%
Cys (C)   3	  0.3%
Gln (Q)  68	  7.7%
Glu (E)  48	  5.5%
Gly (G)  44	  5.0%
His (H)  26	  3.0%
Ile (I)  51	  5.8%
Leu (L)  61	  6.9%
Lys (K)  59	  6.7%
Met (M)  19	  2.2%
Phe (F)  37	  4.2%
Pro (P)  49	  5.6%
Ser (S) 103	 11.7%
Thr (T)  31	  3.5%
Trp (W)   1	  0.1%
Tyr (Y)  32	  3.6%
Val (V)  40	  4.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 85
Total number of positively charged residues (Arg + Lys): 81

Atomic composition:

Carbon      C	      4284
Hydrogen    H	      6673
Nitrogen    N	      1221
Oxygen      O	      1380
Sulfur      S	        22

Formula: C4284H6673N1221O1380S22
Total number of atoms: 13580

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    53305
Abs 0.1% (=1 g/l)   0.544, assuming all pairs of Cys residues form cystines


Ext. coefficient    53180
Abs 0.1% (=1 g/l)   0.542, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 48.69
This classifies the protein as unstable.



Aliphatic index: 68.81

Grand average of hydropathicity (GRAVY): -0.747