ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEMSLRPLLL VFVLGLVSTP STLAQDDPRY TKFLTQHYDA KPKGRDARYC ESMMRRRGLT 

        70         80         90        100        110        120 
SPCKEVNTFI HGNKGSIKAI CGANGSPYGE NLRISQSPFQ ITTCKHTGGS PRPPCRYRAS 

       130        140 
AGFRHVVIAC ENGLPVHFDE SFISL 

References and documentation are available.

Number of amino acids: 145

Molecular weight: 16105.54

Theoretical pI: 9.44

Amino acid composition: 
Ala (A)   8	  5.5%
Arg (R)  12	  8.3%
Asn (N)   5	  3.4%
Asp (D)   5	  3.4%
Cys (C)   6	  4.1%
Gln (Q)   4	  2.8%
Glu (E)   6	  4.1%
Gly (G)  12	  8.3%
His (H)   5	  3.4%
Ile (I)   7	  4.8%
Leu (L)  12	  8.3%
Lys (K)   7	  4.8%
Met (M)   4	  2.8%
Phe (F)   7	  4.8%
Pro (P)  11	  7.6%
Ser (S)  13	  9.0%
Thr (T)   9	  6.2%
Trp (W)   0	  0.0%
Tyr (Y)   5	  3.4%
Val (V)   7	  4.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 11
Total number of positively charged residues (Arg + Lys): 19

Atomic composition:

Carbon      C	       707
Hydrogen    H	      1121
Nitrogen    N	       207
Oxygen      O	       204
Sulfur      S	        10

Formula: C707H1121N207O204S10
Total number of atoms: 2249

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     7825
Abs 0.1% (=1 g/l)   0.486, assuming all pairs of Cys residues form cystines


Ext. coefficient     7450
Abs 0.1% (=1 g/l)   0.463, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 50.38
This classifies the protein as unstable.



Aliphatic index: 70.62

Grand average of hydropathicity (GRAVY): -0.343