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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MENESSESRN RARLAIMELA NMISVPMSLN AAVRLGIADA IWNGGANSPL SAAEILPRLH

70 80 90 100 110 120
LPSHTTIGGD PENLQRILRM LTSYGVFSEH LVGSIERKYS LTDVGKTLVT DSGGLSYAAY

130 140 150 160 170 180
VLQHHQEALM RAWPLVHTAV VEPETEPYVK ANGEAAYAQY GKSEEMNGLM QKAMSGVSVP

190 200 210 220 230 240
FMKAILDGYD GFKSVDILVD VGGSAGDCLR MILQQFPNVR EGINFDLPEV VAKAPNIPGV

250 260 270 280 290 300
THVGGDMFQS VPSADAIFMK WVLTTWTDEE CKQIMKNCYN ALPVGGKLIA CEPVLPKETD

310 320 330 340 350
ESHRTRALLE GDIFVMTIYR TKGKHRTEEE FIELGLSAGF PTFRPFYIDY FYTILEFQK


References and documentation are available.

Number of amino acids: 359 Molecular weight: 39688.48 Theoretical pI: 5.28
Amino acid composition: 
Ala (A) 30 8.4% Arg (R) 16 4.5% Asn (N) 14 3.9% Asp (D) 16 4.5% Cys (C) 4 1.1% Gln (Q) 10 2.8% Glu (E) 28 7.8% Gly (G) 29 8.1% His (H) 9 2.5% Ile (I) 21 5.8% Leu (L) 33 9.2% Lys (K) 16 4.5% Met (M) 15 4.2% Phe (F) 14 3.9% Pro (P) 19 5.3% Ser (S) 23 6.4% Thr (T) 19 5.3% Trp (W) 4 1.1% Tyr (Y) 13 3.6% Val (V) 26 7.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 44 Total number of positively charged residues (Arg + Lys): 32 Atomic composition: Carbon C 1772 Hydrogen H 2773 Nitrogen N 469 Oxygen O 527 Sulfur S 19 Formula: C1772H2773N469O527S19 Total number of atoms: 5560 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41620 Abs 0.1% (=1 g/l) 1.049, assuming all pairs of Cys residues form cystines Ext. coefficient 41370 Abs 0.1% (=1 g/l) 1.042, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.19 This classifies the protein as unstable. Aliphatic index: 88.02 Grand average of hydropathicity (GRAVY): -0.096