ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MENGNSSSDN KSSHKPIRCK AAVSRKAGEP LVMEEIMVAP PQPFEVRIRI ICTALCHSDV 

        70         80         90        100        110        120 
TFWKLQVPPA CFPRILGHEA IGVVESVGEN VKEVVEGDTV LPTFMPDCGD CVDCKSHKSN 

       130        140        150        160        170        180 
LCSKFPFKVS PWMPRYDNSS RFTDLNGETL FHFLNVSSFS EYTVLDVANV VKIDSSIPPS 

       190        200        210        220        230        240 
RACLLSCGVS TGVGAAWETA KVEKGSTVVI FGLGSIGLAV AEGARLCGAS RIIGVDINPT 

       250        260        270        280        290        300 
KFQVGQKFGV TEFVNSMTCE KNRVSEVINE MTDGGADYCF ECVGSSSLVQ EAYACCRQGW 

       310        320        330        340        350        360 
GKTITLGVDK PGSQICLDSF DVLHHGKILM GSLFGGLKAK THIPILLKRY LSNELELDKF 

       370        380        390 
VTHEMKFEEI NDAFQLLLEG KCIRCVLWMG 

References and documentation are available.

Number of amino acids: 390

Molecular weight: 42568.13

Theoretical pI: 5.90

Amino acid composition: 
Ala (A)  21	  5.4%
Arg (R)  14	  3.6%
Asn (N)  15	  3.8%
Asp (D)  18	  4.6%
Cys (C)  19	  4.9%
Gln (Q)   8	  2.1%
Glu (E)  27	  6.9%
Gly (G)  33	  8.5%
His (H)   9	  2.3%
Ile (I)  22	  5.6%
Leu (L)  31	  7.9%
Lys (K)  25	  6.4%
Met (M)  10	  2.6%
Phe (F)  20	  5.1%
Pro (P)  18	  4.6%
Ser (S)  34	  8.7%
Thr (T)  18	  4.6%
Trp (W)   5	  1.3%
Tyr (Y)   5	  1.3%
Val (V)  38	  9.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 45
Total number of positively charged residues (Arg + Lys): 39

Atomic composition:

Carbon      C	      1883
Hydrogen    H	      2977
Nitrogen    N	       503
Oxygen      O	       561
Sulfur      S	        29

Formula: C1883H2977N503O561S29
Total number of atoms: 5953

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    36075
Abs 0.1% (=1 g/l)   0.847, assuming all pairs of Cys residues form cystines


Ext. coefficient    34950
Abs 0.1% (=1 g/l)   0.821, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.75
This classifies the protein as stable.



Aliphatic index: 86.64

Grand average of hydropathicity (GRAVY): 0.043