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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MENKETKQEP AAAAEQKTVP LIEDEIERSK VGIMRALCDR QDPETKEVDD LMIRRFLRAR

70 80 90 100 110 120
DLDIEKASTM FLNYLTWKRS MLPKGHIPEA EIANDLSHNK MCMQGHDKMG RPIAVAIGNR

130 140 150 160 170 180
HNPSKGNPDE FKRFVVYTLE KICARMPRGQ EKFVAIGDLQ GWGYSNCDIR GYLAALSTLQ

190 200 210 220 230 240
DCYPERLGKL YIVHAPYIFM TAWKVIYPFI DANTKKKIVF VENKKLTPTL LEDIDESQLP

250
DIYGGKLPLV PIQET


References and documentation are available.

Number of amino acids: 255 Molecular weight: 29215.84 Theoretical pI: 6.96
Amino acid composition: 
Ala (A) 18 7.1% Arg (R) 15 5.9% Asn (N) 10 3.9% Asp (D) 17 6.7% Cys (C) 5 2.0% Gln (Q) 9 3.5% Glu (E) 20 7.8% Gly (G) 14 5.5% His (H) 5 2.0% Ile (I) 20 7.8% Leu (L) 22 8.6% Lys (K) 22 8.6% Met (M) 10 3.9% Phe (F) 8 3.1% Pro (P) 16 6.3% Ser (S) 8 3.1% Thr (T) 12 4.7% Trp (W) 3 1.2% Tyr (Y) 9 3.5% Val (V) 12 4.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 37 Total number of positively charged residues (Arg + Lys): 37 Atomic composition: Carbon C 1302 Hydrogen H 2074 Nitrogen N 354 Oxygen O 378 Sulfur S 15 Formula: C1302H2074N354O378S15 Total number of atoms: 4123 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 30160 Abs 0.1% (=1 g/l) 1.032, assuming all pairs of Cys residues form cystines Ext. coefficient 29910 Abs 0.1% (=1 g/l) 1.024, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 50.79 This classifies the protein as unstable. Aliphatic index: 84.94 Grand average of hydropathicity (GRAVY): -0.453