ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEPATLTRSS SLTRFPYRRG LSTLRLARVN SFSILPPKTL LRQKPLRISA SLNLPPRSIR 

        70         80         90        100        110        120 
LRAVEDHHHD HHHDDEQDHH NHHHHHHQHG CCSVELKAES KPQKMLFGFA KAIGWVRLAN 

       130        140        150        160        170        180 
YLREHLHLCC SAAAMFLAAA VCPYLAPEPY IKSLQNAFMI VGFPLVGVSA SLDALMDIAG 

       190        200        210        220        230        240 
GKVNIHVLMA LAAFASVFMG NALEGGLLLA MFNLAHIAEE FFTSRSMVDV KELKESNPDS 

       250        260        270        280        290        300 
ALLIEVHNGN VPNISDLSYK SVPVHSVEVG SYVLVGTGEI VPVDCEVYQG SATITIEHLT 

       310        320        330        340        350        360 
GEVKPLEAKA GDRVPGGARN LDGRMIVKAT KAWNDSTLNK IVQLTEEAHS NKPKLQRWLD 

       370        380        390        400        410        420 
EFGENYSKVV VVLSLAIAFL GPFLFKWPFL STAACRGSVY RALGLMVAAS PCALAVAPLA 

       430        440        450        460        470        480 
YATAISSCAR KGILLKGAQV LDALASCHTI AFDKTGTLTT GGLTCKAIEP IYGHQGGTNS 

       490        500        510        520        530        540 
SVITCCIPNC EKEALAVAAA MEKGTTHPIG RAVVDHSVGK DLPSIFVESF EYFPGRGLTA 

       550        560        570        580        590        600 
TVNGVKTVAE ESRLRKASLG SIEFITSLFK SEDESKQIKD AVNASSYGKD FVHAALSVDQ 

       610        620        630        640        650        660 
KVTLIHLEDQ PRPGVSGVIA ELKSWARLRV MMLTGDHDSS AWRVANAVGI TEVYCNLKPE 

       670        680        690        700        710        720 
DKLNHVKNIA REAGGGLIMV GEGINDAPAL AAATVGIVLA QRASATAIAV ADILLLRDNI 

       730        740        750        760        770        780 
TGVPFCVAKS RQTTSLVKQN VALALTSIFL AALPSVLGFV PLWLTVLLHE GGTLLVCLNS 

       790        800        810 
VRGLNDPSWS WKQDIVHLIN KLRSQEPTSS SSNSLSSAH 

References and documentation are available.

Number of amino acids: 819

Molecular weight: 88188.75

Theoretical pI: 8.06

Amino acid composition: 
Ala (A)  91	 11.1%
Arg (R)  35	  4.3%
Asn (N)  32	  3.9%
Asp (D)  32	  3.9%
Cys (C)  17	  2.1%
Gln (Q)  18	  2.2%
Glu (E)  42	  5.1%
Gly (G)  56	  6.8%
His (H)  34	  4.2%
Ile (I)  42	  5.1%
Leu (L)  95	 11.6%
Lys (K)  42	  5.1%
Met (M)  15	  1.8%
Phe (F)  27	  3.3%
Pro (P)  37	  4.5%
Ser (S)  70	  8.5%
Thr (T)  41	  5.0%
Trp (W)   9	  1.1%
Tyr (Y)  14	  1.7%
Val (V)  70	  8.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 74
Total number of positively charged residues (Arg + Lys): 77

Atomic composition:

Carbon      C	      3932
Hydrogen    H	      6289
Nitrogen    N	      1093
Oxygen      O	      1143
Sulfur      S	        32

Formula: C3932H6289N1093O1143S32
Total number of atoms: 12489

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    71360
Abs 0.1% (=1 g/l)   0.809, assuming all pairs of Cys residues form cystines


Ext. coefficient    70360
Abs 0.1% (=1 g/l)   0.798, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.06
This classifies the protein as stable.



Aliphatic index: 101.14

Grand average of hydropathicity (GRAVY): 0.119