Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MEPESIGDVG NHAQDDSASI VSGPRRRSTS KTSSAKNIRN SSNISPASMI FRNLLILEDD

70 80 90 100 110 120
LRRQAHEQKI LKWQFTLFLA SMAGVGAFTF YELYFTSDYV KGLHRVILQF TLSFISITVV

130 140 150 160 170 180
LFHISGQYRR TIVIPRRFFT STNKGIRQFN VKLVKVQSTW DEKYTDSVRF VSRTIAYCNI

190 200 210 220 230 240
YCLKKFLWLK DDNAIVKFWK SVTIQSQPRI GAVDVKLVLN PRAFSAEIRE GWEIYRDEFW

250
AREGARRRKQ AHELRPKSE


References and documentation are available.

Number of amino acids: 259 Molecular weight: 30113.60 Theoretical pI: 10.03
Amino acid composition: 
Ala (A) 16 6.2% Arg (R) 24 9.3% Asn (N) 10 3.9% Asp (D) 12 4.6% Cys (C) 2 0.8% Gln (Q) 11 4.2% Glu (E) 13 5.0% Gly (G) 11 4.2% His (H) 5 1.9% Ile (I) 21 8.1% Leu (L) 19 7.3% Lys (K) 17 6.6% Met (M) 3 1.2% Phe (F) 17 6.6% Pro (P) 7 2.7% Ser (S) 25 9.7% Thr (T) 14 5.4% Trp (W) 6 2.3% Tyr (Y) 8 3.1% Val (V) 18 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 25 Total number of positively charged residues (Arg + Lys): 41 Atomic composition: Carbon C 1362 Hydrogen H 2137 Nitrogen N 385 Oxygen O 378 Sulfur S 5 Formula: C1362H2137N385O378S5 Total number of atoms: 4267 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 45045 Abs 0.1% (=1 g/l) 1.496, assuming all pairs of Cys residues form cystines Ext. coefficient 44920 Abs 0.1% (=1 g/l) 1.492, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 51.83 This classifies the protein as unstable. Aliphatic index: 86.56 Grand average of hydropathicity (GRAVY): -0.321