ProtParam
User-provided sequence:
10
MEPSLDNYKL SC
References and
documentation are available.
Number of amino acids: 12
Molecular weight: 1399.60
Theoretical pI: 4.37
Total number of negatively charged residues (Asp + Glu): 2
Total number of positively charged residues (Arg + Lys): 1
Atomic composition:
Carbon C 59
Hydrogen H 94
Nitrogen N 14
Oxygen O 21
Sulfur S 2
Formula: C
59H
94N
14O
21S
2
Total number of atoms: 190
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 1.065, assuming all pairs of Cys residues form cystines
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 1.065, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 61.36
This classifies the protein as unstable.
Aliphatic index: 65.00
Grand average of hydropathicity (GRAVY): -0.575