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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MERYDRQLRL WGALGQDSLN RSRVCVVGPA TPLLQEVFKN LVLAGISSLT WLKVECAVQS

70 80 90 100 110 120
GSLFLAELKK DLEPLASKQL EYEENDLRKT LQQPQYDWTR FSVVILTCIG EQTAMLDLNE

130 140 150 160 170 180
IRRQRGTKFP PVLNTFVSGF YGYIYLVLSE THFVLQAHPD SKKYDLRLQN PWPELINYVD

190 200 210 220 230 240
TFDLSKMDTA TFSGIPYTVL LMKCIAKLER DGNNGRITID QMKKVLDQIC LPLGNDVIYE

250 260 270 280 290 300
PNYVEAKRYA YLACSQNDCC KELEDLLRNL EISDYGNDWH DTYNYEILTL LLTLKNIAKE

310 320 330 340 350 360
NGELSFQPLT GTLPDMESTT ENYIRLKKLY EVKAKLDKSR VEESLARSKK IVSQDVLETF

370 380 390 400 410 420
CSHYGEVRKI LPPKSDLLGI FSTSNALLDA LVMVQFWEQP AVTAEDKDEF IGLRVDDNYS

430 440 450 460
VMAFFGGAVV QEAIKLITHH YVPIDNLFLY NGINNSSATY KI


References and documentation are available.

Number of amino acids: 462 Molecular weight: 52852.61 Theoretical pI: 5.20
Amino acid composition: 
Ala (A) 24 5.2% Arg (R) 20 4.3% Asn (N) 24 5.2% Asp (D) 30 6.5% Cys (C) 9 1.9% Gln (Q) 20 4.3% Glu (E) 32 6.9% Gly (G) 22 4.8% His (H) 6 1.3% Ile (I) 25 5.4% Leu (L) 63 13.6% Lys (K) 30 6.5% Met (M) 8 1.7% Phe (F) 17 3.7% Pro (P) 18 3.9% Ser (S) 28 6.1% Thr (T) 26 5.6% Trp (W) 6 1.3% Tyr (Y) 23 5.0% Val (V) 31 6.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 62 Total number of positively charged residues (Arg + Lys): 50 Atomic composition: Carbon C 2382 Hydrogen H 3740 Nitrogen N 614 Oxygen O 708 Sulfur S 17 Formula: C2382H3740N614O708S17 Total number of atoms: 7461 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 67770 Abs 0.1% (=1 g/l) 1.282, assuming all pairs of Cys residues form cystines Ext. coefficient 67270 Abs 0.1% (=1 g/l) 1.273, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.85 This classifies the protein as stable. Aliphatic index: 98.94 Grand average of hydropathicity (GRAVY): -0.217