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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MESCFPAMKL NQCTFGLNNE IVSERVSAFW GTQVVKPNHL RTTKLRSAPQ KKIQTNLIRS

70 80 90 100 110 120
VLTPFVDQES HEPLLRTQNA DPKNVASIIL GGGAGTRLFP LTSKRAKPAV PIGGCYRLID

130 140 150 160 170 180
IPMSNCINSG IRKIFILTQF NSFSLNRHLS RTYNFGNGVN FGDGFVEVLA ATQTSGDAGK

190 200 210 220 230 240
KWFQGTADAV RQFIWVFEDA KTKNVEHVLI LSGDHLYRMD YMNFVQKHIE SNADITVSCL

250 260 270 280 290 300
PMDESRASDF GLLKIDQSGK IIQFSEKPKG DDLKAMQVDT SILGLPPKEA AESPYIASMG

310 320 330 340 350 360
VYVFRKEVLL KLLRSSYPTS NDFGSEIIPL AVGEHNVQAF LFNDYWEDIG TIGSFFDANL

370 380 390 400 410 420
ALTEQPPKFQ FYDQKTPFFT SPRFLPPTKV DKCRILDSIV SHGCFLRECS VQHSIVGIRS

430 440 450 460 470 480
RLESGVELQD TMMMGADFYQ TEAEIASLLA EGKVPVGVGQ NTKIKNCIID KNAKIGKNVV

490 500 510
IANADGVEEG DRPEEGFHIR SGITVVLKNA TIRDGLHI


References and documentation are available.

Number of amino acids: 518 Molecular weight: 57469.81 Theoretical pI: 7.15
Amino acid composition: 
Ala (A) 32 6.2% Arg (R) 24 4.6% Asn (N) 27 5.2% Asp (D) 29 5.6% Cys (C) 9 1.7% Gln (Q) 22 4.2% Glu (E) 28 5.4% Gly (G) 39 7.5% His (H) 11 2.1% Ile (I) 39 7.5% Leu (L) 42 8.1% Lys (K) 33 6.4% Met (M) 11 2.1% Phe (F) 31 6.0% Pro (P) 25 4.8% Ser (S) 38 7.3% Thr (T) 28 5.4% Trp (W) 4 0.8% Tyr (Y) 10 1.9% Val (V) 36 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 57 Total number of positively charged residues (Arg + Lys): 57 Atomic composition: Carbon C 2568 Hydrogen H 4048 Nitrogen N 698 Oxygen O 758 Sulfur S 20 Formula: C2568H4048N698O758S20 Total number of atoms: 8092 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 37400 Abs 0.1% (=1 g/l) 0.651, assuming all pairs of Cys residues form cystines Ext. coefficient 36900 Abs 0.1% (=1 g/l) 0.642, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 36.06 This classifies the protein as stable. Aliphatic index: 87.32 Grand average of hydropathicity (GRAVY): -0.176