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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MESQQLSNYP HISHGSACAS VTSKEVHTNQ DPLDVSASKI QEYDKASTKA NSQQTTTPAS

70 80 90 100 110 120
SAVPENPHHA SPQPASVPPP QNGPYPQQCM MTQNQANPSG WSFYGHPSMI PYTPYQMSPM

130 140 150 160 170 180
YFPPGPQSQF PQYPSSVGTP LSTPSPESGN TFTDSSSADS DMTSTKKYVR PPPMLTSPND

190 200 210 220 230 240
FPNWVKTYIK FLQNSNLGGI IPTVNGKPVR PITDDELTFL YNAFQIFAPS QFLPTWVKDI

250 260 270 280 290 300
LSVDYTDIMK ILSKSIEKMQ SDTQEANDIV TLANLQYNGS TPADAFETKV TNIIDRLNNN

310 320 330 340 350 360
GIHINNKVAC QLIMRGLSGE YKFLRYTRHR HLNMTVAELF LDIHAIYEEQ QGSRNSKPNY

370 380 390 400 410 420
RRNPSDEKND SRSYTNTTKP KVIARNPQKT NNSKSKTARA HNVSTSNNSP STDNDSISKS

430 440
TTEPIQLNNK HDLHLRPETY


References and documentation are available.

Number of amino acids: 440 Molecular weight: 49067.49 Theoretical pI: 7.73
Amino acid composition: 
Ala (A) 23 5.2% Arg (R) 14 3.2% Asn (N) 38 8.6% Asp (D) 22 5.0% Cys (C) 3 0.7% Gln (Q) 27 6.1% Glu (E) 16 3.6% Gly (G) 15 3.4% His (H) 13 3.0% Ile (I) 23 5.2% Leu (L) 23 5.2% Lys (K) 25 5.7% Met (M) 12 2.7% Phe (F) 13 3.0% Pro (P) 43 9.8% Ser (S) 52 11.8% Thr (T) 38 8.6% Trp (W) 3 0.7% Tyr (Y) 19 4.3% Val (V) 18 4.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 38 Total number of positively charged residues (Arg + Lys): 39 Atomic composition: Carbon C 2145 Hydrogen H 3323 Nitrogen N 601 Oxygen O 691 Sulfur S 15 Formula: C2145H3323N601O691S15 Total number of atoms: 6775 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 44935 Abs 0.1% (=1 g/l) 0.916, assuming all pairs of Cys residues form cystines Ext. coefficient 44810 Abs 0.1% (=1 g/l) 0.913, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 51.20 This classifies the protein as unstable. Aliphatic index: 57.86 Grand average of hydropathicity (GRAVY): -0.815