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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MESQQLSQNS PTFHGSAYAS VTSKEVPSNQ DPLAVSASNL PEFDRDSTKV NSQQETTPGT

70 80 90 100 110 120
SAVPENHHHV SPQPASVPPP QNGQYQQHGM MTPNKAMASN WAHYQQPSMM TCSHYQTSPA

130 140 150 160 170 180
YYQPDPHYPL PQYIPPLSTS SPDPIGSQDQ HSEVPQAKTK VRNNVLPPHT LTSEENFSTW

190 200 210 220 230 240
VKFYIRFLKN SNLGDIIPND QGEIKRQMTY EEHAYIYNTF QAFAPFHLLP TWVKQILEIN

250 260 270 280 290 300
YSDILTVLCK SVSKMQTNNQ ELKDWIALAN LEYNGSTSAD TFEITVSTII QRLKENNINV

310 320 330 340 350 360
SDRLACQLIL KGLSGDFKYL RNQYRTKTNM KLSQLFAEIQ LIYDENKIMN LNKPSQYKQH

370 380 390 400 410 420
SEYKNVSRTS PNTTNTKVTT RNYHRTNSSK PRAAKAHNIA TSSKFSRVNN DHINESTVSS

430
QYLSDDNELS LRPATERI


References and documentation are available.

Number of amino acids: 438 Molecular weight: 49736.35 Theoretical pI: 7.76
Amino acid composition: 
Ala (A) 24 5.5% Arg (R) 15 3.4% Asn (N) 38 8.7% Asp (D) 17 3.9% Cys (C) 3 0.7% Gln (Q) 33 7.5% Glu (E) 22 5.0% Gly (G) 10 2.3% His (H) 16 3.7% Ile (I) 22 5.0% Leu (L) 30 6.8% Lys (K) 25 5.7% Met (M) 10 2.3% Phe (F) 12 2.7% Pro (P) 32 7.3% Ser (S) 49 11.2% Thr (T) 35 8.0% Trp (W) 4 0.9% Tyr (Y) 21 4.8% Val (V) 20 4.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 39 Total number of positively charged residues (Arg + Lys): 40 Atomic composition: Carbon C 2182 Hydrogen H 3383 Nitrogen N 615 Oxygen O 693 Sulfur S 13 Formula: C2182H3383N615O693S13 Total number of atoms: 6886 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 53415 Abs 0.1% (=1 g/l) 1.074, assuming all pairs of Cys residues form cystines Ext. coefficient 53290 Abs 0.1% (=1 g/l) 1.071, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 49.12 This classifies the protein as unstable. Aliphatic index: 65.02 Grand average of hydropathicity (GRAVY): -0.801