ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MESRTTGPLT TETYDGPTVA FMILGAALVF FMVPGLGFLY SGLARRKSAL ALIWVVLMAT 

        70         80         90        100        110        120 
LVGILQWYFW GYSLAFSKSA PNNKFIGNLD SFGFRNVYGK KFDEDAYPEL AYATFQMMFS 

       130        140        150        160        170        180 
CVNLSIIAGA TAERGRLLPH MVFLFILATI GYCPVTYWIW SPGGWAYQWG VLDWAGGGNI 

       190        200        210        220        230        240 
EILSAVSGFV YSWFLGKRNE KLLINFRPHN VSLVTLGTSI LWFGWLLFNS ASSLSPNLRS 

       250        260        270        280        290        300 
VYAFMNTCLS AITGGMTWCL LDYRSEKKWS TVGLCSGIIS GLVAATPSSG CITLYGSLIQ 

       310        320        330        340        350        360 
GIVAGVVCNF ATKLKYYAKV DDAMDILAEH GVAGVIGLIF NALFGADWVI GMDGTTEHEG 

       370        380        390        400        410        420 
GWVTHNYKQM YKQIAYIAAS IGYTAAVTAI ICFVLGYIPG MRLRISEEAE EAGMDEDQIG 

       430        440        450        460        470        480 
EFAYDYVEVR RDYYLWGVDE DSQRSDVNHR VNNAHLAAER SSSGTNSSSD GNGEMIQSEK 

       490 
ILPIHQEDPA NR 

References and documentation are available.

Number of amino acids: 492

Molecular weight: 54202.12

Theoretical pI: 5.35

Amino acid composition: 
Ala (A)  45	  9.1%
Arg (R)  18	  3.7%
Asn (N)  21	  4.3%
Asp (D)  20	  4.1%
Cys (C)   8	  1.6%
Gln (Q)  10	  2.0%
Glu (E)  23	  4.7%
Gly (G)  50	 10.2%
His (H)   8	  1.6%
Ile (I)  34	  6.9%
Leu (L)  47	  9.6%
Lys (K)  15	  3.0%
Met (M)  15	  3.0%
Phe (F)  25	  5.1%
Pro (P)  14	  2.8%
Ser (S)  39	  7.9%
Thr (T)  26	  5.3%
Trp (W)  16	  3.3%
Tyr (Y)  25	  5.1%
Val (V)  33	  6.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 43
Total number of positively charged residues (Arg + Lys): 33

Atomic composition:

Carbon      C	      2477
Hydrogen    H	      3744
Nitrogen    N	       624
Oxygen      O	       700
Sulfur      S	        23

Formula: C2477H3744N624O700S23
Total number of atoms: 7568

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   125750
Abs 0.1% (=1 g/l)   2.320, assuming all pairs of Cys residues form cystines


Ext. coefficient   125250
Abs 0.1% (=1 g/l)   2.311, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.28
This classifies the protein as stable.



Aliphatic index: 92.80

Grand average of hydropathicity (GRAVY): 0.217