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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MESSQGRRRR PGTVVPGEAA ETDSELSASS SEEELYLGPS GPTRGRPTGL RVAGEAAETD

70 80 90 100 110 120
SEPEPEPTVV PVDLPPLVVQ RDPAETWGTE ETPAMAPARS LLQLRLAESQ TRLDHDVAAA

130 140 150 160 170 180
VSGVYRRAGR DVAALAGRLA AAQATGLAAA HSVRLARGDL CALAERLDIV AGCRLLPDIR

190
GVPGMEPEQD PGPRA


References and documentation are available.

Number of amino acids: 195 Molecular weight: 20397.79 Theoretical pI: 4.84
Amino acid composition: 
Ala (A) 30 15.4% Arg (R) 21 10.8% Asn (N) 0 0.0% Asp (D) 11 5.6% Cys (C) 2 1.0% Gln (Q) 6 3.1% Glu (E) 19 9.7% Gly (G) 18 9.2% His (H) 2 1.0% Ile (I) 2 1.0% Leu (L) 20 10.3% Lys (K) 0 0.0% Met (M) 3 1.5% Phe (F) 0 0.0% Pro (P) 19 9.7% Ser (S) 13 6.7% Thr (T) 11 5.6% Trp (W) 1 0.5% Tyr (Y) 2 1.0% Val (V) 15 7.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 30 Total number of positively charged residues (Arg + Lys): 21 Atomic composition: Carbon C 868 Hydrogen H 1425 Nitrogen N 269 Oxygen O 288 Sulfur S 5 Formula: C868H1425N269O288S5 Total number of atoms: 2855 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 8605 Abs 0.1% (=1 g/l) 0.422, assuming all pairs of Cys residues form cystines Ext. coefficient 8480 Abs 0.1% (=1 g/l) 0.416, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 59.72 This classifies the protein as unstable. Aliphatic index: 81.69 Grand average of hydropathicity (GRAVY): -0.376