ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MESSSVDEST TSTGSICETP AITPAKKSSV GNLYRMGSGS SVVLDSENGV EAESRKLPSS 

        70         80         90        100        110        120 
KYKGVVPQPN GRWGAQIYEK HQRVWLGTFN EEDEAARAYD VAVHRFRRRD AVTNFKDVKM 

       130        140        150        160        170        180 
DEDEVDFLNS HSKSEIVDML RKHTYNEELE QSKRRRNGNG NMTRTLLTSG LSNDGVSTTG 

       190        200        210        220        230        240 
FRSAEALFEK AVTPSDVGKL NRLVIPKHHA EKHFPLPSSN VSVKGVLLNF EDVNGKVWRF 

       250        260        270        280        290        300 
RYSYWNSSQS YVLTKGWSRF VKEKNLRAGD VVSFSRSNGQ DQQLYIGWKS RSGSDLDAGR 

       310        320        330        340 
VLRLFGVNIS PESSRNDVVG NKRVNDTEML SLVCSKKQRI FHAS 

References and documentation are available.

Number of amino acids: 344

Molecular weight: 38597.10

Theoretical pI: 9.39

Amino acid composition: 
Ala (A)  16	  4.7%
Arg (R)  27	  7.8%
Asn (N)  22	  6.4%
Asp (D)  19	  5.5%
Cys (C)   2	  0.6%
Gln (Q)   9	  2.6%
Glu (E)  23	  6.7%
Gly (G)  25	  7.3%
His (H)   8	  2.3%
Ile (I)   8	  2.3%
Leu (L)  24	  7.0%
Lys (K)  24	  7.0%
Met (M)   6	  1.7%
Phe (F)  13	  3.8%
Pro (P)  10	  2.9%
Ser (S)  44	 12.8%
Thr (T)  16	  4.7%
Trp (W)   6	  1.7%
Tyr (Y)   9	  2.6%
Val (V)  33	  9.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 42
Total number of positively charged residues (Arg + Lys): 51

Atomic composition:

Carbon      C	      1679
Hydrogen    H	      2658
Nitrogen    N	       502
Oxygen      O	       529
Sulfur      S	         8

Formula: C1679H2658N502O529S8
Total number of atoms: 5376

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    46535
Abs 0.1% (=1 g/l)   1.206, assuming all pairs of Cys residues form cystines


Ext. coefficient    46410
Abs 0.1% (=1 g/l)   1.202, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 46.89
This classifies the protein as unstable.



Aliphatic index: 68.75

Grand average of hydropathicity (GRAVY): -0.693