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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
METEVPAPVR THSYALDRYV RQKRREKQRK QSLKRVEKKY TPSELALYEI RKYQRSTDLL

70 80 90 100 110 120
ISKIPFARLV KEVTDEFTTK DQDLRWQSMA IMALQEASEA YLVGLLEHTN LLALHAKRIT

130
IMKKDMQLAR RIRGQFI


References and documentation are available.

Number of amino acids: 137 Molecular weight: 16293.04 Theoretical pI: 10.03
Amino acid composition: 
Ala (A) 11 8.0% Arg (R) 15 10.9% Asn (N) 1 0.7% Asp (D) 6 4.4% Cys (C) 0 0.0% Gln (Q) 9 6.6% Glu (E) 11 8.0% Gly (G) 2 1.5% His (H) 3 2.2% Ile (I) 8 5.8% Leu (L) 16 11.7% Lys (K) 13 9.5% Met (M) 5 3.6% Phe (F) 3 2.2% Pro (P) 4 2.9% Ser (S) 7 5.1% Thr (T) 9 6.6% Trp (W) 1 0.7% Tyr (Y) 6 4.4% Val (V) 7 5.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 17 Total number of positively charged residues (Arg + Lys): 28 Atomic composition: Carbon C 724 Hydrogen H 1194 Nitrogen N 212 Oxygen O 204 Sulfur S 5 Formula: C724H1194N212O204S5 Total number of atoms: 2339 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 14440 Abs 0.1% (=1 g/l) 0.886 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 59.19 This classifies the protein as unstable. Aliphatic index: 91.17 Grand average of hydropathicity (GRAVY): -0.629