ProtParam
User-provided sequence:
10 20 30 40 50 60
METEVPAPVR THSYALDRYV RQKRREKQRK QSLKRVEKKY TPSELALYEI RKYQRSTDLL
70 80 90 100 110 120
ISKIPFARLV KEVTDEFTTK DQDLRWQSMA IMALQEASEA YLVGLLEHTN LLALHAKRIT
130
IMKKDMQLAR RIRGQFI
References and
documentation are available.
Number of amino acids: 137
Molecular weight: 16293.04
Theoretical pI: 10.03
Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 28
Atomic composition:
Carbon C 724
Hydrogen H 1194
Nitrogen N 212
Oxygen O 204
Sulfur S 5
Formula: C
724H
1194N
212O
204S
5
Total number of atoms: 2339
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 14440
Abs 0.1% (=1 g/l) 0.886
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 59.19
This classifies the protein as unstable.
Aliphatic index: 91.17
Grand average of hydropathicity (GRAVY): -0.629